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https://doi.org/10.1186/s13058-016-0787-0
DC Field | Value | |
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dc.title | Mammographic density assessed on paired raw and processed digital images and on paired screen-film and digital images across three mammography systems | |
dc.contributor.author | Burton, A | |
dc.contributor.author | Byrnes, G | |
dc.contributor.author | Stone, J | |
dc.date.accessioned | 2020-11-17T06:42:03Z | |
dc.date.available | 2020-11-17T06:42:03Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Burton, A, Byrnes, G, Stone, J (2016). Mammographic density assessed on paired raw and processed digital images and on paired screen-film and digital images across three mammography systems. Breast Cancer Research 18 (1) : 130. ScholarBank@NUS Repository. https://doi.org/10.1186/s13058-016-0787-0 | |
dc.identifier.issn | 1465-5411 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/183584 | |
dc.description.abstract | Background: Inter-women and intra-women comparisons of mammographic density (MD) are needed in research, clinical and screening applications; however, MD measurements are influenced by mammography modality (screen film/digital) and digital image format (raw/processed). We aimed to examine differences in MD assessed on these image types. Methods: We obtained 1294 pairs of images saved in both raw and processed formats from Hologic and General Electric (GE) direct digital systems and a Fuji computed radiography (CR) system, and 128 screen-film and processed CR-digital pairs from consecutive screening rounds. Four readers performed Cumulus-based MD measurements (n=3441), with each image pair read by the same reader. Multi-level models of square-root percent MD were fitted, with a random intercept for woman, to estimate processed-raw MD differences. Results: Breast area did not differ in processed images compared with that in raw images, but the percent MD was higher, due to a larger dense area (median 28.5 and 25.4cm2 respectively, mean ?dense area difference 0.44cm (95% CI: 0.36, 0.52)). This difference in ?dense area was significant for direct digital systems (Hologic 0.50cm (95% CI: 0.39, 0.61), GE 0.56cm (95% CI: 0.42, 0.69)) but not for Fuji CR (0.06cm (95% CI: 0.10, 0.23)). Additionally, within each system, reader-specific differences varied in magnitude and direction (p<0.001). Conversion equations revealed differences converged to zero with increasing dense area. MD differences between screen-film and processed digital on the subsequent screening round were consistent with expected time-related MD declines. Conclusions: MD was slightly higher when measured on processed than on raw direct digital mammograms. Comparisons of MD on these image formats should ideally control for this non-constant and reader-specific difference. © 2016 The Author(s). | |
dc.publisher | BioMed Central Ltd. | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.source | Unpaywall 20201031 | |
dc.subject | adult | |
dc.subject | Article | |
dc.subject | breast cancer | |
dc.subject | breast density | |
dc.subject | computer assisted radiography | |
dc.subject | controlled study | |
dc.subject | digital imaging | |
dc.subject | female | |
dc.subject | human | |
dc.subject | image display | |
dc.subject | image processing | |
dc.subject | image quality | |
dc.subject | intermethod comparison | |
dc.subject | mammography | |
dc.subject | mammography system | |
dc.subject | measurement | |
dc.subject | X ray film | |
dc.subject | aged | |
dc.subject | breast tumor | |
dc.subject | diagnostic imaging | |
dc.subject | image processing | |
dc.subject | mammography | |
dc.subject | middle aged | |
dc.subject | pathology | |
dc.subject | procedures | |
dc.subject | very elderly | |
dc.subject | Adult | |
dc.subject | Aged | |
dc.subject | Aged, 80 and over | |
dc.subject | Breast Density | |
dc.subject | Breast Neoplasms | |
dc.subject | Female | |
dc.subject | Humans | |
dc.subject | Image Processing, Computer-Assisted | |
dc.subject | Mammography | |
dc.subject | Middle Aged | |
dc.type | Article | |
dc.contributor.department | SURGERY | |
dc.contributor.department | SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH | |
dc.description.doi | 10.1186/s13058-016-0787-0 | |
dc.description.sourcetitle | Breast Cancer Research | |
dc.description.volume | 18 | |
dc.description.issue | 1 | |
dc.description.page | 130 | |
dc.published.state | Published | |
Appears in Collections: | Elements Staff Publications |
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