1. ScholarBank@NUS
  2. 1. Staff
  3. Staff Publications
Please use this identifier to cite or link to this item: https://doi.org/10.1186/gm388
DC FieldValue
dc.titlePredicting cancer drivers: are we there yet?
dc.contributor.authorKrishnan, V.G
dc.contributor.authorNg, P.C
dc.date.accessioned2020-10-28T07:28:27Z
dc.date.available2020-10-28T07:28:27Z
dc.date.issued2012
dc.identifier.citationKrishnan, V.G, Ng, P.C (2012). Predicting cancer drivers: are we there yet?. Genome Medicine 4 (11) : 88. ScholarBank@NUS Repository. https://doi.org/10.1186/gm388
dc.identifier.issn1756994X
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/181841
dc.description.abstractGenomic variants with a key role in causing cancer or affecting the response to cancertherapeutics need to be identified so that they can be targeted for therapy. The transFIC tool aimsto identify somatic point mutations that drive cancer in sequencing projects. This package isavailable as a web service, a stand-alone program and a website. It improves the functionalprediction scores generated by popular established prediction tools and will be useful to cancerresearchers.See research article: http://genomemedicine.com/content/4/11/89. © 2012 BioMed Central Ltd.
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceUnpaywall 20201031
dc.subjectB Raf kinase
dc.subjectcetuximab
dc.subjectpanitumumab
dc.subjectprotein p53
dc.subjectcancer cell
dc.subjectcancer research
dc.subjectcancer therapy
dc.subjectcell cycle
dc.subjectcolorectal cancer
dc.subjectcost
dc.subjectdriver mutation
dc.subjectdrug sensitivity
dc.subjectgene function
dc.subjectgene mutation
dc.subjectgene product
dc.subjectgene sequence
dc.subjectgenetic correlation
dc.subjectgenetic variability
dc.subjectgerm line
dc.subjecthuman
dc.subjectloss of function mutation
dc.subjectmelanoma
dc.subjectmetastasis
dc.subjectmissense mutation
dc.subjectneoplasm
dc.subjectnote
dc.subjectnucleic acid base substitution
dc.subjectoncogene K ras
dc.subjectpassenger mutation
dc.subjectpoint mutation
dc.subjectprediction
dc.subjectpriority journal
dc.subjectprotein function
dc.subjectscientist
dc.subjectsingle nucleotide polymorphism
dc.subjectsomatic mutation
dc.subjecttreatment outcome
dc.subjecttumor growth
dc.typeNote
dc.contributor.departmentMEDICINE
dc.description.doi10.1186/gm388
dc.description.sourcetitleGenome Medicine
dc.description.volume4
dc.description.issue11
dc.description.page88
Appears in Collections:Staff Publications
Elements

Show simple item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1186_gm388.pdf135.65 kBAdobe PDF

OPEN

NoneView/Download

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons