Please use this identifier to cite or link to this item:
https://doi.org/10.1186/1471-2334-11-212
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dc.title | Could peak proteinuria determine whether patient with dengue fever develop dengue hemorrhagic/dengue shock syndrome? - A prospective cohort study | |
dc.contributor.author | Vasanwala, F.F | |
dc.contributor.author | Puvanendran, R | |
dc.contributor.author | Fook-Chong, S | |
dc.contributor.author | Ng, J | |
dc.contributor.author | Suhail, S.M | |
dc.contributor.author | Lee, K | |
dc.date.accessioned | 2020-10-27T11:31:31Z | |
dc.date.available | 2020-10-27T11:31:31Z | |
dc.date.issued | 2011 | |
dc.identifier.citation | Vasanwala, F.F, Puvanendran, R, Fook-Chong, S, Ng, J, Suhail, S.M, Lee, K (2011). Could peak proteinuria determine whether patient with dengue fever develop dengue hemorrhagic/dengue shock syndrome? - A prospective cohort study. BMC Infectious Diseases 11 : 212. ScholarBank@NUS Repository. https://doi.org/10.1186/1471-2334-11-212 | |
dc.identifier.issn | 14712334 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/181629 | |
dc.description.abstract | Background: Worldwide there is a need to develop simple effective predictors that can distinguish whether a patient will progress from dengue fever (DF) to life threatening dengue hemorrhagic (DHF) or dengue shock syndrome (DSS). We explored whether proteinuria could be used as such a marker.Methods: We included patients admitted to hospital with suspected dengue fever. Starting at enrollment until discharge, each patient's daily spot urine protein creatinine ratio (UPCR) was measured. We classified those with confirmed dengue infection as DF or DHF (including DSS) based on WHO criteria. Peak and day of onset of proteinuria was compared between both groups.Results: Compared to those with DF, patients with DHF had significantly higher median peak proteinuria levels (0.56 versus 0.08 g/day; p < 0.001). For patients with DHF, the median day of onset of proteinuria was at 6 days of defervescence, with a range of -2 to +3 days after defervescence. There were three patients with DF who did not have proteinuria during their illness; the five remaining patients with DF had a median day of onset of proteinuria of was at 6 days of defervescence with a range of 0 to +28 days.Conclusions: Peak UPCR could potentially predict DHF in patients with dengue requiring close monitoring and treatment. © 2011 Vasanwala et al; licensee BioMed Central Ltd. | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.source | Unpaywall 20201031 | |
dc.subject | creatinine | |
dc.subject | protein | |
dc.subject | creatinine | |
dc.subject | adult | |
dc.subject | analytical parameters | |
dc.subject | article | |
dc.subject | clinical article | |
dc.subject | cohort analysis | |
dc.subject | controlled study | |
dc.subject | dengue | |
dc.subject | dengue shock syndrome | |
dc.subject | disease classification | |
dc.subject | disease marker | |
dc.subject | hospital admission | |
dc.subject | hospital discharge | |
dc.subject | human | |
dc.subject | onset age | |
dc.subject | prospective study | |
dc.subject | proteinuria | |
dc.subject | urine protein creatinine ratio | |
dc.subject | chemistry | |
dc.subject | evaluation | |
dc.subject | middle aged | |
dc.subject | prognosis | |
dc.subject | proteinuria | |
dc.subject | urine | |
dc.subject | Adult | |
dc.subject | Cohort Studies | |
dc.subject | Creatinine | |
dc.subject | Dengue Hemorrhagic Fever | |
dc.subject | Humans | |
dc.subject | Middle Aged | |
dc.subject | Prognosis | |
dc.subject | Prospective Studies | |
dc.subject | Proteinuria | |
dc.subject | Urine | |
dc.type | Article | |
dc.contributor.department | DUKE-NUS MEDICAL SCHOOL | |
dc.description.doi | 10.1186/1471-2334-11-212 | |
dc.description.sourcetitle | BMC Infectious Diseases | |
dc.description.volume | 11 | |
dc.description.page | 212 | |
Appears in Collections: | Elements Staff Publications |
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