Please use this identifier to cite or link to this item:
https://doi.org/10.1186/s13059-016-0951-y
DC Field | Value | |
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dc.title | OPERA-LG: Efficient and exact scaffolding of large, repeat-rich eukaryotic genomes with performance guarantees | |
dc.contributor.author | Gao, S | |
dc.contributor.author | Bertrand, D | |
dc.contributor.author | Chia, B.K.H | |
dc.contributor.author | Nagarajan, N | |
dc.date.accessioned | 2020-10-27T10:43:05Z | |
dc.date.available | 2020-10-27T10:43:05Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Gao, S, Bertrand, D, Chia, B.K.H, Nagarajan, N (2016). OPERA-LG: Efficient and exact scaffolding of large, repeat-rich eukaryotic genomes with performance guarantees. Genome Biology 17 (1) : 102. ScholarBank@NUS Repository. https://doi.org/10.1186/s13059-016-0951-y | |
dc.identifier.issn | 14747596 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/181369 | |
dc.description.abstract | The assembly of large, repeat-rich eukaryotic genomes represents a significant challenge in genomics. While long-read technologies have made the high-quality assembly of small, microbial genomes increasingly feasible, data generation can be expensive for larger genomes. OPERA-LG is a scalable, exact algorithm for the scaffold assembly of large, repeat-rich genomes, out-performing state-of-the-art programs for scaffold correctness and contiguity. It provides a rigorous framework for scaffolding of repetitive sequences and a systematic approach for combining data from different second-generation and third-generation sequencing technologies. OPERA-LG provides an avenue for systematic augmentation and improvement of thousands of existing draft eukaryotic genome assemblies. © 2016 Gao et al. | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.source | Unpaywall 20201031 | |
dc.subject | eukaryote | |
dc.subject | genomics | |
dc.subject | microbial genome | |
dc.subject | animal | |
dc.subject | contig mapping | |
dc.subject | DNA sequence | |
dc.subject | genome size | |
dc.subject | nucleotide repeat | |
dc.subject | procedures | |
dc.subject | software | |
dc.subject | Animals | |
dc.subject | Contig Mapping | |
dc.subject | Genome Size | |
dc.subject | Repetitive Sequences, Nucleic Acid | |
dc.subject | Sequence Analysis, DNA | |
dc.subject | Software | |
dc.type | Article | |
dc.contributor.department | MEDICINE | |
dc.description.doi | 10.1186/s13059-016-0951-y | |
dc.description.sourcetitle | Genome Biology | |
dc.description.volume | 17 | |
dc.description.issue | 1 | |
dc.description.page | 102 | |
Appears in Collections: | Elements Staff Publications |
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