1. ScholarBank@NUS
  2. 1. Staff
  3. Staff Publications
Please use this identifier to cite or link to this item: https://doi.org/10.1186/s12916-014-0130-5
DC FieldValue
dc.titleCardiovascular risk factors and future risk of Alzheimer's disease
dc.contributor.authorde Bruijn, R.F.A.G
dc.contributor.authorIkram, M.A
dc.date.accessioned2020-10-27T05:54:47Z
dc.date.available2020-10-27T05:54:47Z
dc.date.issued2014
dc.identifier.citationde Bruijn, R.F.A.G, Ikram, M.A (2014). Cardiovascular risk factors and future risk of Alzheimer's disease. BMC Medicine 12 (1) : 130. ScholarBank@NUS Repository. https://doi.org/10.1186/s12916-014-0130-5
dc.identifier.issn17417015
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/180969
dc.description.abstractAlzheimer's disease (AD) is the most common neurodegenerative disorder in elderly people, but there are still no curative options. Senile plaques and neurofibrillary tangles are considered hallmarks of AD, but cerebrovascular pathology is also common. In this review, we summarize findings on cardiovascular disease (CVD) and risk factors in the etiology of AD. Firstly, we discuss the association of clinical CVD (such as stroke and heart disease) and AD. Secondly, we summarize the relation between imaging makers of pre-clinical vascular disease and AD. Lastly, we discuss the association of cardiovascular risk factors and AD. We discuss both established cardiovascular risk factors and emerging putative risk factors, which exert their effect partly via CVD. © 2014 de Bruijn and Ikram.
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceUnpaywall 20201031
dc.subjecthomocysteine
dc.subjectthyroid hormone
dc.subjectAlzheimer disease
dc.subjectarterial stiffness
dc.subjectArticle
dc.subjectblood pressure
dc.subjectbrain atrophy
dc.subjectbrain hemorrhage
dc.subjectcardiovascular disease
dc.subjectcardiovascular risk
dc.subjectcerebrovascular accident
dc.subjectcerebrovascular disease
dc.subjectchronic kidney disease
dc.subjectcognitive defect
dc.subjectdementia
dc.subjectdiffusion tensor imaging
dc.subjectdisease association
dc.subjectdisease marker
dc.subjectfunctional magnetic resonance imaging
dc.subjectglucose metabolism
dc.subjectheart atrium fibrillation
dc.subjectheart disease
dc.subjectheart failure
dc.subjecthuman
dc.subjecthypercholesterolemia
dc.subjecthypertension
dc.subjectinflammation
dc.subjectischemic heart disease
dc.subjectMediterranean diet
dc.subjectnon insulin dependent diabetes mellitus
dc.subjectobesity
dc.subjectphysical activity
dc.subjectpulse wave
dc.subjectrisk assessment
dc.subjectsmoking
dc.subjectthyroid function
dc.subjectwhite matter lesion
dc.subjectaged
dc.subjectAlzheimer disease
dc.subjectamyloid plaque
dc.subjectcardiovascular disease
dc.subjectcomplication
dc.subjectneurofibrillary tangle
dc.subjectpathology
dc.subjectrisk factor
dc.subjectAged
dc.subjectAlzheimer Disease
dc.subjectCardiovascular Diseases
dc.subjectHumans
dc.subjectNeurofibrillary Tangles
dc.subjectPlaque, Amyloid
dc.subjectRisk Factors
dc.typeArticle
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.description.doi10.1186/s12916-014-0130-5
dc.description.sourcetitleBMC Medicine
dc.description.volume12
dc.description.issue1
dc.description.page130
Appears in Collections:Staff Publications
Elements

Show simple item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1186_s12916-014-0130-5.pdf975.58 kBAdobe PDF

OPEN

NoneView/Download

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons