Please use this identifier to cite or link to this item: https://doi.org/10.1007/s10561-014-9469-2
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dc.titleBanking of cryopreserved iliac artery and vein homografts: clinical uses in transplantation
dc.contributor.authorHeng, W.L
dc.contributor.authorMadhavan, K
dc.contributor.authorWee, P
dc.contributor.authorSeck, T
dc.contributor.authorLim, Y.P
dc.contributor.authorLim, C.H
dc.date.accessioned2020-10-23T08:13:40Z
dc.date.available2020-10-23T08:13:40Z
dc.date.issued2015
dc.identifier.citationHeng, W.L, Madhavan, K, Wee, P, Seck, T, Lim, Y.P, Lim, C.H (2015). Banking of cryopreserved iliac artery and vein homografts: clinical uses in transplantation. Cell and Tissue Banking 16 (2) : 235-242. ScholarBank@NUS Repository. https://doi.org/10.1007/s10561-014-9469-2
dc.identifier.issn1389-9333
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/179661
dc.description.abstractIliac artery and vein homografts are critical for revascularization in living-donor liver transplantation. Since 2010, National Cardiovascular Homograft Bank and National University Hospital have collaborated in the pioneer endeavor of banking iliac vessel homografts for such surgeries in Singapore. This article aims to demonstrate that the processing, decontamination and cryopreservation techniques that our bank follow, help preserve iliac vessel homografts for a longer duration as compared to homografts preserved using short-term preservation techniques. This paper reports the first 4 years of post-operative outcome for recipients as a preliminary report for a longer-term outcome study. Criteria for donor assessment, techniques of iliac vessel homograft recovery, processing, decontamination, cryopreservation and storage according to the American Association of Tissue Banks standards are also described. From 2010 until 2013, we discovered of the iliac vessel homografts processed, 17 (94.4 %) were suitable for clinical use. Nine iliac artery grafts (64 %) and one iliac vein graft (14 %) were implanted. Irrespective of vessel type, homografts <90 mm in length were of little use. Of the nine current iliac vessel homograft recipients, eight patients (89 %) had living-donor liver transplantation and one patient (11 %) had reconstruction of the right internal carotid artery after resection of an aneurysm. Our preliminary results supports existing literatures that suggest cryopreserved iliac vessel homografts can be successfully used for revascularization in liver transplantation and reconstruction of carotid artery. Encouraging short-term post-operative patient outcomes have been achieved, with no report of adverse event attributed to implanted homografts. We believe that our processing, decontamination and cryopreservation techniques have helped preserve the homografts for longer duration as compared to homografts preserved using short-term preservation techniques. © 2014, The Author(s).
dc.publisherKluwer Academic Publishers
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceUnpaywall 20201031
dc.subjectadolescent
dc.subjectadult
dc.subjectaged
dc.subjectallograft
dc.subjectallotransplantation
dc.subjectchild
dc.subjectcryopreservation
dc.subjectcytology
dc.subjecthuman
dc.subjectiliac artery
dc.subjectiliac vein
dc.subjectliver transplantation
dc.subjectmiddle aged
dc.subjectprocedures
dc.subjectstandards
dc.subjecttissue bank
dc.subjecttransplantation
dc.subjectyoung adult
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectAllografts
dc.subjectChild
dc.subjectCryopreservation
dc.subjectHumans
dc.subjectIliac Artery
dc.subjectIliac Vein
dc.subjectLiver Transplantation
dc.subjectMiddle Aged
dc.subjectTissue Banks
dc.subjectTransplantation, Homologous
dc.subjectYoung Adult
dc.typeArticle
dc.contributor.departmentDEPT OF SURGERY
dc.description.doi10.1007/s10561-014-9469-2
dc.description.sourcetitleCell and Tissue Banking
dc.description.volume16
dc.description.issue2
dc.description.page235-242
dc.published.statePublished
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