Please use this identifier to cite or link to this item: https://doi.org/10.1055/s-2005-861030
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dc.titleA hypothetical index of hypothalamic-pituitary-adrenal (HPA) axis function
dc.contributor.authorLeow M.K.S.
dc.date.accessioned2020-10-15T03:01:12Z
dc.date.available2020-10-15T03:01:12Z
dc.date.issued2005
dc.identifier.citationLeow M.K.S. (2005). A hypothetical index of hypothalamic-pituitary-adrenal (HPA) axis function. Hormone and Metabolic Research 37 (1) : 1-3. ScholarBank@NUS Repository. https://doi.org/10.1055/s-2005-861030
dc.identifier.issn00185043
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/177456
dc.description.abstractThe short ACTH stimulation test (SST) is commonly used by clinicians to determine the integrity of the hypothalamic-pituitary-adrenal (HPA) axis in cases of suspected adrenal insufficiency. Concern has arisen for under-diagnosis of central hypocortisolism using the standard dose (250mcg) SST with the recent introduction of low-dose (1mcg) SST as a potentially more sensitive test for central hypocortisolism. Amidst this uncertainty, I will present a novel index hypothesized to extend the sensitivity of the standard dose SST as an adjunctive diagnostic tool for any level of hypocortisolism.
dc.sourceScopus
dc.subjectAdrenocortical insufficiency
dc.subjectCorticotropin stimulation test
dc.subjectMathematical model
dc.typeArticle
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.description.doi10.1055/s-2005-861030
dc.description.sourcetitleHormone and Metabolic Research
dc.description.volume37
dc.description.issue1
dc.description.page1-3
dc.published.statePublished
Appears in Collections:Staff Publications

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