Please use this identifier to cite or link to this item: https://doi.org/10.1186/s13613-017-0343-9
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dc.titleFrequency and prognostic impact of basic critical care echocardiography abnormalities in patients with acute respiratory distress syndrome
dc.contributor.authorSee, K.C
dc.contributor.authorNg, J
dc.contributor.authorSiow, W.T
dc.contributor.authorOng, V
dc.contributor.authorPhua, J
dc.date.accessioned2020-09-14T07:57:20Z
dc.date.available2020-09-14T07:57:20Z
dc.date.issued2017
dc.identifier.citationSee, K.C, Ng, J, Siow, W.T, Ong, V, Phua, J (2017). Frequency and prognostic impact of basic critical care echocardiography abnormalities in patients with acute respiratory distress syndrome. Annals of Intensive Care 7 (1) : 120. ScholarBank@NUS Repository. https://doi.org/10.1186/s13613-017-0343-9
dc.identifier.issn2110-5820
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/176067
dc.description.abstractBackground: Among intensive care unit (ICU) patients with acute respiratory distress syndrome (ARDS), apart from acute cor pulmonale (ACP), the frequency and prognostic impact of basic critical care echocardiography (BCCE) abnormalities are not well defined. Methods: Observational study of patients with ARDS, admitted from September 2012 to May 2014, who underwent BCCE within 48 h of admission to a 20-bed medical ICU. We examined the association of two major BCCE-detected abnormalities (left ventricular ejection fraction < 40% and severe ACP) with ICU/hospital mortality and ICU/hospital length of stay. Multivariable models adjusted for age and illness severity. Results: Of 234 patients with ARDS (age 62.3 ± 14.3 years; 88/37.6% female; APACHE II 26.8 ± 8.3; 26.5% ICU mortality; 32.1% hospital mortality), 94 (40.2%) had at least one major BCCE-detected abnormality. The more common major BCCE abnormality found was severe ACP (28.2%), followed by left ventricular ejection fraction < 40% (16.2%). On multivariate analysis, only severe ACP remained significantly associated with ICU/hospital mortality. Hospital mortality for mild, moderate and severe ARDS was 17.0, 27.9 and 50.0%, respectively (without severe ACP), and was 29.2, 48.3 and 53.8%, respectively (with severe ACP). Conclusions: BCCE abnormalities were common, but only severe ACP had prognostic significance in ARDS, identifying patients who are at increased risk of ICU and hospital mortality. The presence of severe ACP appears to upstage ARDS severity by one level. © 2017, The Author(s).
dc.sourceUnpaywall 20200831
dc.subjectadult
dc.subjectadult respiratory distress syndrome
dc.subjectAPACHE
dc.subjectArticle
dc.subjectbasic critical care echocardiography
dc.subjectcomparative study
dc.subjectcontrolled study
dc.subjectcor pulmonale
dc.subjectdisease severity
dc.subjectechocardiography
dc.subjectfemale
dc.subjectheart ejection fraction
dc.subjectheart left ventricle ejection fraction
dc.subjecthospital mortality
dc.subjecthuman
dc.subjectintensive care
dc.subjectintensive care unit
dc.subjectlength of stay
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmiddle aged
dc.subjectobservational study
dc.subjectpriority journal
dc.subjectprospective study
dc.subjecttransthoracic echocardiography
dc.typeArticle
dc.contributor.departmentMEDICINE
dc.description.doi10.1186/s13613-017-0343-9
dc.description.sourcetitleAnnals of Intensive Care
dc.description.volume7
dc.description.issue1
dc.description.page120
dc.published.statePublished
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