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Please use this identifier to cite or link to this item: https://doi.org/10.1128/AAC.00682-13
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dc.titleField-based flow cytometry for ex vivo characterization of plasmodium vivax and P. falciparum antimalarial sensitivity
dc.contributor.authorRussell B.
dc.contributor.authorMalleret B.
dc.contributor.authorSuwanarusk R.
dc.contributor.authorAnthony C.
dc.contributor.authorKanlaya S.
dc.contributor.authorLau Y.L.
dc.contributor.authorWoodrow C.J.
dc.contributor.authorNosten F.
dc.contributor.authorRenia L.
dc.date.accessioned2020-09-09T09:44:09Z
dc.date.available2020-09-09T09:44:09Z
dc.date.issued2013
dc.identifier.citationRussell B., Malleret B., Suwanarusk R., Anthony C., Kanlaya S., Lau Y.L., Woodrow C.J., Nosten F., Renia L. (2013). Field-based flow cytometry for ex vivo characterization of plasmodium vivax and P. falciparum antimalarial sensitivity. Antimicrobial Agents and Chemotherapy 57 (10) : 5170-5174. ScholarBank@NUS Repository. https://doi.org/10.1128/AAC.00682-13
dc.identifier.issn0066-4804
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/175329
dc.description.abstractEx vivo antimalarial sensitivity testing in human malaria parasites has largely depended on microscopic determination of schizont maturation. While this microscopic method is sensitive, it suffers from poor precision and is laborious. The recent development of portable, low-cost cytometers has allowed us to develop and validate a simple, field-optimized protocol using SYBR green and dihydroethidium for the accurate and objective determination of antimalarial drug sensitivity in freshly isolated Plasmodium vivax and Plasmodium falciparum. Copyright © 2013, American Society for Microbiology. All Rights Reserved.
dc.sourceUnpaywall 20200831
dc.subjectartesunate
dc.subjectchloroquine
dc.subjectfluorescent dye
dc.subjecthydroethidine
dc.subjectantimalarial drug susceptibility
dc.subjectarticle
dc.subjectclinical protocol
dc.subjectcontrolled study
dc.subjectex vivo study
dc.subjectflow cytometry
dc.subjectGiemsa stain
dc.subjecthuman
dc.subjectIC 50
dc.subjectmajor clinical study
dc.subjectmicroscopy
dc.subjectparasitemia
dc.subjectPlasmodium falciparum
dc.subjectPlasmodium vivax
dc.subjectpriority journal
dc.subjectAntimalarials
dc.subjectFlow Cytometry
dc.subjectPlasmodium falciparum
dc.subjectPlasmodium vivax
dc.typeArticle
dc.contributor.departmentMICROBIOLOGY AND IMMUNOLOGY
dc.description.doi10.1128/AAC.00682-13
dc.description.sourcetitleAntimicrobial Agents and Chemotherapy
dc.description.volume57
dc.description.issue10
dc.description.page5170-5174
dc.published.statePublished
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