Please use this identifier to cite or link to this item: https://doi.org/10.1038/NMETH.4470
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dc.titleDeciphering lipid structures based on platform-independent decision rules
dc.contributor.authorHartler, Juergen
dc.contributor.authorTriebl, Alexander
dc.contributor.authorZiegl, Andreas
dc.contributor.authorTroetzmueller, Martin
dc.contributor.authorRechberger, Gerald N
dc.contributor.authorZeleznik, Oana A
dc.contributor.authorZierler, Kathrin A
dc.contributor.authorTorta, Federico
dc.contributor.authorCazenave-Gassiot, Amaury
dc.contributor.authorWenk, Markus R
dc.contributor.authorFauland, Alexander
dc.contributor.authorWheelock, Craig E
dc.contributor.authorArmando, Aaron M
dc.contributor.authorQuehenberger, Oswald
dc.contributor.authorZhang, Qifeng
dc.contributor.authorWakelam, Michael JO
dc.contributor.authorHaemmerle, Guenter
dc.contributor.authorSpener, Friedrich
dc.contributor.authorKoefeler, Harald C
dc.contributor.authorThallinger, Gerhard G
dc.date.accessioned2020-07-01T05:45:33Z
dc.date.available2020-07-01T05:45:33Z
dc.date.issued2017-12-01
dc.identifier.citationHartler, Juergen, Triebl, Alexander, Ziegl, Andreas, Troetzmueller, Martin, Rechberger, Gerald N, Zeleznik, Oana A, Zierler, Kathrin A, Torta, Federico, Cazenave-Gassiot, Amaury, Wenk, Markus R, Fauland, Alexander, Wheelock, Craig E, Armando, Aaron M, Quehenberger, Oswald, Zhang, Qifeng, Wakelam, Michael JO, Haemmerle, Guenter, Spener, Friedrich, Koefeler, Harald C, Thallinger, Gerhard G (2017-12-01). Deciphering lipid structures based on platform-independent decision rules. NATURE METHODS 14 (12) : 1171-1174. ScholarBank@NUS Repository. https://doi.org/10.1038/NMETH.4470
dc.identifier.issn15487091
dc.identifier.issn15487105
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/170836
dc.description.abstract© 2017 Nature America, Inc., part of Springer Nature. All rights reserved. We achieve automated and reliable annotation of lipid species and their molecular structures in high-throughput data from chromatography-coupled tandem mass spectrometry using decision rule sets embedded in Lipid Data Analyzer (LDA; http://genome.tugraz.at/lda2). Using various low- and high-resolution mass spectrometry instruments with several collision energies, we proved the method's platform independence. We propose that the software's reliability, flexibility, and ability to identify novel lipid molecular species may now render current state-of-the-art lipid libraries obsolete.
dc.language.isoen
dc.publisherNATURE PUBLISHING GROUP
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectBiochemical Research Methods
dc.subjectBiochemistry & Molecular Biology
dc.subjectTANDEM MASS-SPECTROMETRY
dc.subjectSHOTGUN LIPIDOMICS
dc.subjectIDENTIFICATION
dc.subjectDATABASE
dc.subjectMETABOLOMICS
dc.subjectIONIZATION
dc.subjectMECHANISMS
dc.subjectPROTEOMICS
dc.typeArticle
dc.date.updated2020-06-17T03:30:05Z
dc.contributor.departmentDEPT OF BIOCHEMISTRY
dc.description.doi10.1038/NMETH.4470
dc.description.sourcetitleNATURE METHODS
dc.description.volume14
dc.description.issue12
dc.description.page1171-1174
dc.published.statePublished
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