Please use this identifier to cite or link to this item: https://doi.org/10.1039/c6tb01159d
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dc.titleDecoration of porphyrin with tetraphenylethene: converting a fluorophore with aggregation-caused quenching to aggregation-induced emission enhancement
dc.contributor.authorGUO BING
dc.contributor.authorCAI XIAOLEI
dc.contributor.authorXU SHIDANG
dc.contributor.authorFateminia, Syed Mohammad Ali
dc.contributor.authorLIU JIE
dc.contributor.authorLIANG JING
dc.contributor.authorFENG GUANGXUE
dc.contributor.authorWu, Wenbo
dc.contributor.authorLIU BIN
dc.date.accessioned2020-06-11T08:39:17Z
dc.date.available2020-06-11T08:39:17Z
dc.date.issued2016-01-01
dc.identifier.citationGUO BING, CAI XIAOLEI, XU SHIDANG, Fateminia, Syed Mohammad Ali, LIU JIE, LIANG JING, FENG GUANGXUE, Wu, Wenbo, LIU BIN (2016-01-01). Decoration of porphyrin with tetraphenylethene: converting a fluorophore with aggregation-caused quenching to aggregation-induced emission enhancement. Journal of Materials Chemistry B 4 (27) : 4690-4695. ScholarBank@NUS Repository. https://doi.org/10.1039/c6tb01159d
dc.identifier.issn2050-750X
dc.identifier.issn2050-7518
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/169673
dc.description.abstractPorphyrins have long been used as fluorescence imaging contrast agents. However, they often suffer from aggregation-caused quenching (ACQ) which limits their maximal imaging ability. It is desirable to design new porphyrin derivatives exhibiting aggregation induced emission enhancement (AIEE) with a high photoluminescence (PL) intensity in an aggregated state. Herein, we transform porphyrin from an ACQ molecule to an AIEE one by simply decorating a porphyrin core with four tetraphenylethene arms. We further encapsulate the new AIE porphyrin into nanoparticles and examine their fluorescence imaging in vitro with HeLa cells. This research demonstrates a general approach to produce AIEE porphyrin derivatives that could potentially enhance their performance in various areas.
dc.language.isoen
dc.publisherRoyal Society of Chemistry
dc.sourceElements
dc.subjectScience & Technology
dc.subjectTechnology
dc.subjectMaterials Science, Biomaterials
dc.subjectMaterials Science
dc.subjectFLUORESCENT ORGANIC NANOPARTICLES
dc.subjectPHOTODYNAMIC THERAPY
dc.subjectIN-VIVO
dc.subjectPROTOPORPHYRIN-IX
dc.subjectDRUG-DELIVERY
dc.subjectOXYGEN
dc.subjectMICELLES
dc.subjectRESECTION
dc.subjectCOPOLYMER
dc.subjectHYDROGEL
dc.typeArticle
dc.date.updated2020-06-10T09:09:52Z
dc.contributor.departmentDEPT OF CHEMICAL & BIOMOLECULAR ENGG
dc.description.doi10.1039/c6tb01159d
dc.description.sourcetitleJournal of Materials Chemistry B
dc.description.volume4
dc.description.issue27
dc.description.page4690-4695
dc.published.statePublished
dc.grant.idR279-000-444-281
dc.grant.fundingagencyNational Research Foundation Singapore
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