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https://scholarbank.nus.edu.sg/handle/10635/156376
Title: | GENETIC VARIATION IN TIME PREFERENCES | Authors: | JOVI LOO LEK YANG | Keywords: | Time-preferences genetics biology |
Issue Date: | 8-Apr-2019 | Citation: | JOVI LOO LEK YANG (2019-04-08). GENETIC VARIATION IN TIME PREFERENCES. ScholarBank@NUS Repository. | Abstract: | Objective: Time preferences are important in understanding many economic phenomena ranging from an individual’s choice to procrastinate to saving patterns of a macro-economy. This paper studies the role of three genes – Retinoic Acid Receptor Alpha (RAR?), Selenium Binding Protein 1 (SELENBP1), and Adrenergic Receptor Genes (ADR) – in predicting one’s level of impatience and present bias. Methodology: A total of 3510 Han Chinese participants from Singapore and Beijing took part in this study. Time-preferences were elicited from incentivised near-term and remote-future tasks. Sequence variation information was collected from all participants, while gene expression data was collected only for a subset of Singaporean participants. Results: Gene expression of RAR? was found to be positively corelated with remote-future impatience and negatively correlated with present bias. Expression of SELENBP1 was found to be negatively correlated with both near-future impatience and present bias. Expression of ADRB1 (Beta-1 Adrenergic Receptor) was found to be positively correlated to both near and remote-term impatience. Additionally, a total of 6 SNPs (Single Nucleotide Polymorphisms) belonging to ADRA1B (Alpha-1B Adrenergic Receptor) and ADRB2 (Beta-2 Adrenergic Receptor) were found to be significantly associated with various time-preferences phenotype. | URI: | https://scholarbank.nus.edu.sg/handle/10635/156376 |
Appears in Collections: | Bachelor's Theses |
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Jovi Loo Lek Yang AY1819 Sem 2.pdf | 649.09 kB | Adobe PDF | RESTRICTED | None | Log In |
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