Please use this identifier to cite or link to this item:
https://doi.org/10.1002/acr.23834
DC Field | Value | |
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dc.title | American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus | |
dc.contributor.author | Brunner, Hermine I | |
dc.contributor.author | Holland, Michael J | |
dc.contributor.author | Beresford, Michael W | |
dc.contributor.author | Ardoin, Stacy P | |
dc.contributor.author | Appenzeller, Simone | |
dc.contributor.author | Silva, Clovis A | |
dc.contributor.author | Flores, Francisco | |
dc.contributor.author | Goilav, Beatrice | |
dc.contributor.author | Aydin, Pinar Ozge Avar | |
dc.contributor.author | Wenderfer, Scott E | |
dc.contributor.author | Levy, Deborah M | |
dc.contributor.author | Kingsbury, Daniel | |
dc.contributor.author | Lai, Jamie | |
dc.contributor.author | Lovell, Daniel | |
dc.contributor.author | Nanda, Kabita | |
dc.contributor.author | Nocton, James | |
dc.contributor.author | Olson, Judyann | |
dc.contributor.author | O'Neil, Kathleen | |
dc.contributor.author | Onel, Karen | |
dc.contributor.author | Punaro, Lynn | |
dc.contributor.author | Brusco, Maria Isabel | |
dc.contributor.author | Aviel, Yonatan Butbul | |
dc.contributor.author | Rouster-Stevens, Andreas Reiff Kelly | |
dc.contributor.author | Ruth, Natasha | |
dc.contributor.author | Schikler, Ken | |
dc.contributor.author | Schmidt, Kara Murphy | |
dc.contributor.author | Schulert, Grant | |
dc.contributor.author | Shaham, Bracha | |
dc.contributor.author | Singer, Nora | |
dc.contributor.author | Smith, Judith | |
dc.contributor.author | Sundel, Robert | |
dc.contributor.author | Syverson, Grant | |
dc.contributor.author | Cimaz, Rolando | |
dc.contributor.author | Cuttica, Ruben | |
dc.contributor.author | Vega-Fernandez, Patricia | |
dc.contributor.author | Vehe, Richard | |
dc.contributor.author | Wagner-Weiner, Linda | |
dc.contributor.author | Cameto, Juan | |
dc.contributor.author | Jurado, Rosario | |
dc.contributor.author | Maldonado, Irama | |
dc.contributor.author | De Cunto, Carmen | |
dc.contributor.author | Espada, Graciela | |
dc.contributor.author | Farfan, Maximiliano | |
dc.contributor.author | Maggio, Maria Cristina | |
dc.contributor.author | Garay, Stella | |
dc.contributor.author | Marcantoni, Maria | |
dc.contributor.author | Marcela, Alvarez | |
dc.contributor.author | Meiorin, Silvia | |
dc.contributor.author | Rama, Maria Elena | |
dc.contributor.author | Russo, Ricardo | |
dc.contributor.author | Walsh, Carolina Torre | |
dc.contributor.author | Zamparo, Celso | |
dc.contributor.author | Adib, Navid | |
dc.contributor.author | Akikusa, Jonathan | |
dc.contributor.author | Rumba-Rozenfelde, Ingrid | |
dc.contributor.author | Boros, Christina | |
dc.contributor.author | Lee, Senq J | |
dc.contributor.author | Mckay, Damien | |
dc.contributor.author | Piper, Susan | |
dc.contributor.author | Joos, Rik | |
dc.contributor.author | Bica, Blanca | |
dc.contributor.author | Campos, Leonardo | |
dc.contributor.author | Cavalcanti, Andre | |
dc.contributor.author | do Prado, Rogerio | |
dc.contributor.author | Donner-Maliki, Amanda | |
dc.contributor.author | Hashad, Soad | |
dc.contributor.author | Fernandes, Taciana | |
dc.contributor.author | Fonseca, Adriana | |
dc.contributor.author | de Almeida, Rozana Gasparello | |
dc.contributor.author | Guariento, Andressa | |
dc.contributor.author | Gusman, Catherine | |
dc.contributor.author | Fiorot, Fernanda Jusan | |
dc.contributor.author | Oliveira, Sheila Knupp | |
dc.contributor.author | Len, Claudio | |
dc.contributor.author | Campos, Lucia M Arruda | |
dc.contributor.author | Machado, Sandra | |
dc.contributor.author | Lim, Sern Chin | |
dc.contributor.author | Marques, Luciana | |
dc.contributor.author | de Carvalho, Luciana Martins | |
dc.contributor.author | Moulin, Rodrigo | |
dc.contributor.author | Pedroso, Soraya | |
dc.contributor.author | Pileggi, Gecilmara | |
dc.contributor.author | Romanelli, Paulo Roberto S | |
dc.contributor.author | Saad-Magalhaes, Claudia | |
dc.contributor.author | Sakamoto, Ana | |
dc.contributor.author | Santos, Maria Carolina | |
dc.contributor.author | Silva, Marco Felipe | |
dc.contributor.author | Abud, Carlos | |
dc.contributor.author | Spelling, Paulo | |
dc.contributor.author | Sztajnbok, Slavio | |
dc.contributor.author | Terreri, Maria | |
dc.contributor.author | Cabral, David | |
dc.contributor.author | Chedeville, Gaelle | |
dc.contributor.author | Ellsworth, Janet | |
dc.contributor.author | Huber, Adam | |
dc.contributor.author | Tucker, Lori | |
dc.contributor.author | Houghton, Kristin | |
dc.contributor.author | Borzutzky, Arturo | |
dc.contributor.author | Burgos-Vargas, Ruben | |
dc.contributor.author | Ladino, Mabel | |
dc.contributor.author | Norambuena, Ximena | |
dc.contributor.author | Eraso, Ruth | |
dc.contributor.author | Mosquera, Angela | |
dc.contributor.author | Velasquez, Monica | |
dc.contributor.author | Harjacek, Miroslav | |
dc.contributor.author | Jelusic, Marija | |
dc.contributor.author | Hermosilla, Cecilia Coto | |
dc.contributor.author | Dolezalova, Pavla | |
dc.contributor.author | Nielsen, Susan | |
dc.contributor.author | Carreno-Manjarrez, Roberto | |
dc.contributor.author | Tineo, Carmen | |
dc.contributor.author | Alegria, Mauricio | |
dc.contributor.author | Dressler, Frank | |
dc.contributor.author | Foell, Dirk | |
dc.contributor.author | Ganser, Gerd | |
dc.contributor.author | Hinze, Claas | |
dc.contributor.author | Hufnagel, Markus | |
dc.contributor.author | Lutz, Thomas | |
dc.contributor.author | Trauzeddel, Ralf | |
dc.contributor.author | Boiu, Sorina | |
dc.contributor.author | Enciso Pelaez, Sandra | |
dc.contributor.author | Trachana, Maria | |
dc.contributor.author | Tsitsami, Elena | |
dc.contributor.author | Cifuentes, Mayra | |
dc.contributor.author | Orban, Ilonka | |
dc.contributor.author | Aggarwal, Amita | |
dc.contributor.author | Sawhney, Sujata | |
dc.contributor.author | Ravelli, Angelo | |
dc.contributor.author | Hernandez-Huirache, Hayde | |
dc.contributor.author | Maldonado Velazquez, Rocio | |
dc.contributor.author | Orozco, Javier | |
dc.contributor.author | Rodriguez-Lozano, Ana Luisa | |
dc.contributor.author | Rojas Pacheco, Omar Ernesto | |
dc.contributor.author | Suarez Larios, Luz Maria | |
dc.contributor.author | Vega, Gabriel | |
dc.contributor.author | Ramirez Miramontes, Julia Veronica | |
dc.contributor.author | Ruiz Lopez, Ivon Karina | |
dc.contributor.author | Kamphuis, Sylvia | |
dc.contributor.author | Khubchandani, Raju | |
dc.contributor.author | Schonenberg-Meinema, Dieneke | |
dc.contributor.author | Concannon, Anthony | |
dc.contributor.author | Yan, Jaqueline | |
dc.contributor.author | Jaime, Martha Jarquin | |
dc.contributor.author | Al Abrawi, Safiya | |
dc.contributor.author | Vega, Cynthia | |
dc.contributor.author | Lopez-Benitez, Jorge | |
dc.contributor.author | Estrella, Amparo Ibanez | |
dc.contributor.author | Miraval, Tatiana | |
dc.contributor.author | Dans, Leonia | |
dc.contributor.author | Avcin, Tadej | |
dc.contributor.author | Kimseng, Karen Joy | |
dc.contributor.author | Opoka-Winiarska, Violetta | |
dc.contributor.author | Rutkowska-Sak, Lidia | |
dc.contributor.author | Smolewska, Elzbieta | |
dc.contributor.author | Conde, Marta | |
dc.contributor.author | Guedes, Margarida | |
dc.contributor.author | del Valle, Enid | |
dc.contributor.author | Quintero-Del Rio, Ana | |
dc.contributor.author | Ailioaie, Constantin | |
dc.contributor.author | Sparchez, Mihaela | |
dc.contributor.author | Klein-Gitelman, Marisa S | |
dc.contributor.author | Alekseeva, Ekaterina | |
dc.contributor.author | Keltsev, Vladimir | |
dc.contributor.author | Al-Mayouf, Sulaiman | |
dc.contributor.author | Asiri, Abdurhman | |
dc.contributor.author | Suwairi, Wafaa | |
dc.contributor.author | Susic, Gordana | |
dc.contributor.author | Vijatov-Djuric, Gordana | |
dc.contributor.author | Ang, Elizabeth | |
dc.contributor.author | Arkachaisri, Thaschawee | |
dc.contributor.author | Boteanu, Alina-Lucica | |
dc.contributor.author | Ruperto, Nicolino | |
dc.contributor.author | Lopez-Robledillo, Juan Carlos | |
dc.contributor.author | San Ildefonso, Marta Medrano | |
dc.contributor.author | Modesto, Consuelo | |
dc.contributor.author | Calvo, Inmaculada | |
dc.contributor.author | Sotoca-Fernandez, Jorge | |
dc.contributor.author | Bolt, Isabel | |
dc.contributor.author | Vilaiyuk, Soamarat | |
dc.contributor.author | Al-Abadi, Eslam | |
dc.contributor.author | Baildam, Eileen | |
dc.contributor.author | Fotis, Lampros | |
dc.contributor.author | Feldman, Brian M | |
dc.contributor.author | Pain, Clare | |
dc.contributor.author | Pilkington, Clarissa | |
dc.contributor.author | Abulaban, Khalid | |
dc.contributor.author | Barbar-Smiley, Fatima | |
dc.contributor.author | Binstadt, Bryce | |
dc.contributor.author | Bohnsack, John | |
dc.contributor.author | Boneparth, Alexis | |
dc.contributor.author | Brown, Diane | |
dc.contributor.author | Chira, Peter | |
dc.contributor.author | Cron, Randy | |
dc.contributor.author | Ying, Jun | |
dc.contributor.author | Dedeoglu, Fatma | |
dc.contributor.author | Eberhard, Anne | |
dc.contributor.author | Gedalia, Abraham | |
dc.contributor.author | Grom, Alexei | |
dc.contributor.author | Goilav, Beatrice | |
dc.contributor.author | Henrickson, Michael | |
dc.contributor.author | Hom, Christine | |
dc.contributor.author | Huggins, Jennifer | |
dc.contributor.author | Jerath, Rita | |
dc.contributor.author | Jones, Jordan | |
dc.contributor.author | Battagliotti, Cristina | |
dc.contributor.author | Jung, Lawrence | |
dc.date.accessioned | 2019-06-07T01:54:01Z | |
dc.date.available | 2019-06-07T01:54:01Z | |
dc.date.issued | 2019-05-01 | |
dc.identifier.citation | Brunner, Hermine I, Holland, Michael J, Beresford, Michael W, Ardoin, Stacy P, Appenzeller, Simone, Silva, Clovis A, Flores, Francisco, Goilav, Beatrice, Aydin, Pinar Ozge Avar, Wenderfer, Scott E, Levy, Deborah M, Kingsbury, Daniel, Lai, Jamie, Lovell, Daniel, Nanda, Kabita, Nocton, James, Olson, Judyann, O'Neil, Kathleen, Onel, Karen, Punaro, Lynn, Brusco, Maria Isabel, Aviel, Yonatan Butbul, Rouster-Stevens, Andreas Reiff Kelly, Ruth, Natasha, Schikler, Ken, Schmidt, Kara Murphy, Schulert, Grant, Shaham, Bracha, Singer, Nora, Smith, Judith, Sundel, Robert, Syverson, Grant, Cimaz, Rolando, Cuttica, Ruben, Vega-Fernandez, Patricia, Vehe, Richard, Wagner-Weiner, Linda, Cameto, Juan, Jurado, Rosario, Maldonado, Irama, De Cunto, Carmen, Espada, Graciela, Farfan, Maximiliano, Maggio, Maria Cristina, Garay, Stella, Marcantoni, Maria, Marcela, Alvarez, Meiorin, Silvia, Rama, Maria Elena, Russo, Ricardo, Walsh, Carolina Torre, Zamparo, Celso, Adib, Navid, Akikusa, Jonathan, Rumba-Rozenfelde, Ingrid, Boros, Christina, Lee, Senq J, Mckay, Damien, Piper, Susan, Joos, Rik, Bica, Blanca, Campos, Leonardo, Cavalcanti, Andre, do Prado, Rogerio, Donner-Maliki, Amanda, Hashad, Soad, Fernandes, Taciana, Fonseca, Adriana, de Almeida, Rozana Gasparello, Guariento, Andressa, Gusman, Catherine, Fiorot, Fernanda Jusan, Oliveira, Sheila Knupp, Len, Claudio, Campos, Lucia M Arruda, Machado, Sandra, Lim, Sern Chin, Marques, Luciana, de Carvalho, Luciana Martins, Moulin, Rodrigo, Pedroso, Soraya, Pileggi, Gecilmara, Romanelli, Paulo Roberto S, Saad-Magalhaes, Claudia, Sakamoto, Ana, Santos, Maria Carolina, Silva, Marco Felipe, Abud, Carlos, Spelling, Paulo, Sztajnbok, Slavio, Terreri, Maria, Cabral, David, Chedeville, Gaelle, Ellsworth, Janet, Huber, Adam, Tucker, Lori, Houghton, Kristin, Borzutzky, Arturo, Burgos-Vargas, Ruben, Ladino, Mabel, Norambuena, Ximena, Eraso, Ruth, Mosquera, Angela, Velasquez, Monica, Harjacek, Miroslav, Jelusic, Marija, Hermosilla, Cecilia Coto, Dolezalova, Pavla, Nielsen, Susan, Carreno-Manjarrez, Roberto, Tineo, Carmen, Alegria, Mauricio, Dressler, Frank, Foell, Dirk, Ganser, Gerd, Hinze, Claas, Hufnagel, Markus, Lutz, Thomas, Trauzeddel, Ralf, Boiu, Sorina, Enciso Pelaez, Sandra, Trachana, Maria, Tsitsami, Elena, Cifuentes, Mayra, Orban, Ilonka, Aggarwal, Amita, Sawhney, Sujata, Ravelli, Angelo, Hernandez-Huirache, Hayde, Maldonado Velazquez, Rocio, Orozco, Javier, Rodriguez-Lozano, Ana Luisa, Rojas Pacheco, Omar Ernesto, Suarez Larios, Luz Maria, Vega, Gabriel, Ramirez Miramontes, Julia Veronica, Ruiz Lopez, Ivon Karina, Kamphuis, Sylvia, Khubchandani, Raju, Schonenberg-Meinema, Dieneke, Concannon, Anthony, Yan, Jaqueline, Jaime, Martha Jarquin, Al Abrawi, Safiya, Vega, Cynthia, Lopez-Benitez, Jorge, Estrella, Amparo Ibanez, Miraval, Tatiana, Dans, Leonia, Avcin, Tadej, Kimseng, Karen Joy, Opoka-Winiarska, Violetta, Rutkowska-Sak, Lidia, Smolewska, Elzbieta, Conde, Marta, Guedes, Margarida, del Valle, Enid, Quintero-Del Rio, Ana, Ailioaie, Constantin, Sparchez, Mihaela, Klein-Gitelman, Marisa S, Alekseeva, Ekaterina, Keltsev, Vladimir, Al-Mayouf, Sulaiman, Asiri, Abdurhman, Suwairi, Wafaa, Susic, Gordana, Vijatov-Djuric, Gordana, Ang, Elizabeth, Arkachaisri, Thaschawee, Boteanu, Alina-Lucica, Ruperto, Nicolino, Lopez-Robledillo, Juan Carlos, San Ildefonso, Marta Medrano, Modesto, Consuelo, Calvo, Inmaculada, Sotoca-Fernandez, Jorge, Bolt, Isabel, Vilaiyuk, Soamarat, Al-Abadi, Eslam, Baildam, Eileen, Fotis, Lampros, Feldman, Brian M, Pain, Clare, Pilkington, Clarissa, Abulaban, Khalid, Barbar-Smiley, Fatima, Binstadt, Bryce, Bohnsack, John, Boneparth, Alexis, Brown, Diane, Chira, Peter, Cron, Randy, Ying, Jun, Dedeoglu, Fatma, Eberhard, Anne, Gedalia, Abraham, Grom, Alexei, Goilav, Beatrice, Henrickson, Michael, Hom, Christine, Huggins, Jennifer, Jerath, Rita, Jones, Jordan, Battagliotti, Cristina, Jung, Lawrence (2019-05-01). American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus. ARTHRITIS CARE & RESEARCH 71 (5) : 579-590. ScholarBank@NUS Repository. https://doi.org/10.1002/acr.23834 | |
dc.identifier.issn | 2151464X | |
dc.identifier.issn | 21514658 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/155343 | |
dc.description.abstract | © 2019, American College of Rheumatology Objective: To develop a Childhood Lupus Improvement Index (CHILI) as a tool to measure response to therapy in childhood-onset systemic lupus erythematosus (cSLE), with a focus on clinically relevant improvement (CRI cSLE ). Methods: Pediatric nephrology and rheumatology subspecialists (n = 213) experienced in cSLE management were invited to define CRI cSLE and rate a total of 433 unique patient profiles for the presence/absence of CRI cSLE . Patient profiles included the following cSLE core response variables (CRVs): global assessment of patient well-being (patient-global), physician assessment of cSLE activity (MD-global), disease activity index score (here, we used the Systemic Lupus Erythematosus Disease Activity Index), urine protein-to-creatinine ratio, and Child Health Questionnaire physical summary score. Percentage and absolute changes in these cSLE-CRVs (baseline versus follow-up) were considered in order to develop candidate algorithms and validate their performance (sensitivity, specificity, area under the receiver operating characteristic curve [AUC]; range 0–1). Results: During an international consensus conference, unanimous agreement on a definition of CRI cSLE was achieved; cSLE experts (n = 13) concurred (100%) that the preferred CHILI algorithm considers absolute changes in the cSLE-CRVs. After transformation to a range of 0–100, a CHILI score of ≥54 had outstanding accuracy for identifying CRI cSLE (AUC 0.93, sensitivity 81.1%, and specificity 84.2%). CHILI scores also reflect minor, moderate, and major improvement for values exceeding 15, 68, and 92, respectively (all AUC ≥0.92, sensitivity ≥93.1%, and specificity ≥73.4%). Conclusion: The CHILI is a new, seemingly highly accurate index for measuring CRI in cSLE over time. This index is useful to categorize the degree of response to therapy in children and adolescents with cSLE. | |
dc.language.iso | en | |
dc.publisher | WILEY | |
dc.source | Elements | |
dc.subject | Science & Technology | |
dc.subject | Life Sciences & Biomedicine | |
dc.subject | Rheumatology | |
dc.subject | OUTCOME MEASUREMENT SETS | |
dc.subject | DISEASE-ACTIVITY INDEX | |
dc.subject | PROSPECTIVE VALIDATION | |
dc.subject | OMERACT FILTER | |
dc.subject | GLOBAL FLARES | |
dc.subject | THERAPY | |
dc.subject | CLASSIFICATION | |
dc.subject | DEFINITION | |
dc.subject | REMISSION | |
dc.type | Article | |
dc.date.updated | 2019-06-03T23:27:57Z | |
dc.contributor.department | DUKE-NUS MEDICAL SCHOOL | |
dc.description.doi | 10.1002/acr.23834 | |
dc.description.sourcetitle | ARTHRITIS CARE & RESEARCH | |
dc.description.volume | 71 | |
dc.description.issue | 5 | |
dc.description.page | 579-590 | |
dc.published.state | Published | |
Appears in Collections: | Staff Publications Elements |
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