Please use this identifier to cite or link to this item: https://doi.org/10.1002/mds.20246
Title: Nurr1 mutational screen in Parkinson's disease
Authors: Tan E.-K. 
Chung H.
Chandran V.R.
Tan C.
Shen H.
Yew K.
Pavanni R. 
Puvan K.-A. 
Wong M.-C. 
Teoh M.-L.
Yih Y.
Zhao Y.
Keywords: Mutation
Nurr1
Parkinson's disease
Polymorphism
Issue Date: 2004
Publisher: Wiley
Citation: Tan E.-K., Chung H., Chandran V.R., Tan C., Shen H., Yew K., Pavanni R., Puvan K.-A., Wong M.-C., Teoh M.-L., Yih Y., Zhao Y. (2004). Nurr1 mutational screen in Parkinson's disease. Movement Disorders 19 (12) : 1503-1505. ScholarBank@NUS Repository. https://doi.org/10.1002/mds.20246
Abstract: We performed sequence analysis of all the exons and exon-intron boundaries in familial and young-onset Parkinson's disease (PD) in an Asian cohort. None of the patients carried any pathogenic mutations in the Nurr1 gene. We demonstrated a 5 to 10% prevalence of the intron 7 +33 C?T variant among Malay and Indian PD and healthy controls, suggesting that this variant, which was previously described only in 1 Chinese patient, was not a silent mutation but a common polymorphic variant in some ethnic races. 2004 Movement Disorder Society.
Source Title: Movement Disorders
URI: http://scholarbank.nus.edu.sg/handle/10635/150235
ISSN: 08853185
DOI: 10.1002/mds.20246
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