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|Title:||Systemic Lupus Erythematosus: Initial Manifestations and Clinical Features after 10 Years of Disease||Authors:||Fong, K.Y.
|Issue Date:||May-1997||Citation:||Fong, K.Y., Thumboo, J., Koh, E.T., Chng, H.H., Leong, K.H., Koh, W.H., Howe, H.S., Leong, K.P., Lim, E., Koh, D.R., Ng, S.C., Feng, P.H., Boey, M.L. (1997-05). Systemic Lupus Erythematosus: Initial Manifestations and Clinical Features after 10 Years of Disease. Annals of the Academy of Medicine Singapore 26 (3) : 278-281. ScholarBank@NUS Repository.||Abstract:||We studied the initial manifestations and late features in our lupus patients. The clinical data of patients fulfilling the American College of Rheumatology criteria for systemic lupus erythematosus (SLE) were entered prospectively for newly diagnosed patients and cumulatively for those with at least 10 years of disease duration. Ninety-seven Group A (newly diagnosed; 86 females and 11 males; mean age 31 years; 83 Chinese, 11 Malays, and 3 Indians) and 58 Group B (more than 10 years disease duration; 56 females and 2 males; mean age 41 years; 50 Chinese, 5 Malays, and 3 Indians) lupus patients were studied. The commonest clinical features in Group A were: haematological (73%), arthritis (57%), malar rash (43%), renal disorder (31%) and photosensitivity (30%). Group B patients had haematological (78%), malar rash (73%), arthritis (69%), renal disorder (59%) and photosensitivity (33%). Renal disorder was significantly increased over the years (P||Source Title:||Annals of the Academy of Medicine Singapore||URI:||http://scholarbank.nus.edu.sg/handle/10635/133999||ISSN:||03044602|
|Appears in Collections:||Staff Publications|
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