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Title: Quality assessment of two lactate test strip methods suitable for obstetric use
Authors: Nordström, L.
Chua, S. 
Roy, A.C. 
Arulkumaran, S. 
Keywords: Fetal distress
Metabolic acidosis
Test strip meter
Issue Date: 1998
Citation: Nordström, L., Chua, S., Roy, A.C., Arulkumaran, S. (1998). Quality assessment of two lactate test strip methods suitable for obstetric use. Journal of Perinatal Medicine 26 (2) : 83-88. ScholarBank@NUS Repository.
Abstract: Accuracy of lactate determinations in cord blood was tested for one reflectometric (Accusport®) and one amperometric (Lactate Pro®) microvolume test strip lactate meter. Both meters, using a whole blood sample, measure lower levels of lactate than a reflectometric device considered as a reference method, which analyses lactate in plasma. Readings were unaffected irrespective of lactate concentrations for the Lactate Pro®, whilst the Accusport® overestimated low lactate concentrations and underestimated high values. Both lactate meters underestimated lactate concentrations at high hematocrits, as compared with the reference method. The Lactate Pro® has a fixed sample volume of 5 μl while the Accusport® uses random blood drop as sample volume. However, in analyses with less than 20 μl sample volume considerable underestimation was found with the Accusport®. Coefficient of variation was 3.8-8.9% for the Accusport® and 3.1-4.0% for the Lactate Pro® within lactate concentrations between 2.1 and 5.3 mmol/l. The amperometric device, the Lactate Pro® performed best in these tests dealing with fetal blood lactate concentrations. The new technique can be a useful tool in perinatal research as well as in obstetric practice.
Source Title: Journal of Perinatal Medicine
ISSN: 03005577
Appears in Collections:Staff Publications

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