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Title: The glucose challenge test: a screening test for gestational diabetes mellitus.
Authors: Chua, S. 
Thai, A.C. 
Kek, L.P.
Yeoh, S.C. 
Ratnam, S.S. 
Issue Date: Aug-1993
Citation: Chua, S., Thai, A.C., Kek, L.P., Yeoh, S.C., Ratnam, S.S. (1993-08). The glucose challenge test: a screening test for gestational diabetes mellitus.. Singapore Medical Journal 34 (4) : 303-305. ScholarBank@NUS Repository.
Abstract: The 50g glucose challenge test (GCT) was evaluated as a method to screen for gestational diabetes in 540 low-risk pregnant women to establish its sensitivity and specificity, as well as to establish a relevant threshold plasma glucose value above which a diagnostic 75g oral glucose tolerance test (OGTT) would be indicated. If a threshold of 140 mg/dl is used, the diagnostic yield would be 28.5%. At a threshold of 130 mg/dl, the diagnostic yield fell to 25.4%; the sensitivity rose to 87.7% and the specificity declined to 67.1%. There was progressive increase in diagnostic sensitivity when the GCT was performed after 24 weeks without significant decrease in specificity. In low-risk populations, a 50g GCT should be performed between 24-28 weeks gestation.
Source Title: Singapore Medical Journal
ISSN: 00375675
Appears in Collections:Staff Publications

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