Please use this identifier to cite or link to this item:
|Title:||Studies on human filariasis in Malaysia: Immunodiagnosis using indirect immunofluorescence||Authors:||Singh, M.
|Issue Date:||1979||Citation:||Singh, M., Kane, G.J., Yap, E.H., Ho, B.C., Mak, J.W., Kang, K.L. (1979). Studies on human filariasis in Malaysia: Immunodiagnosis using indirect immunofluorescence. Southeast Asian Journal of Tropical Medicine and Public Health 10 (4) : 486-497. ScholarBank@NUS Repository.||Abstract:||The indirect immunofluorescence test using sonicated microfilariae of Brugia malayi has been evaluated on 173 sera from patients and persons exposed to Wuchereria bancrofti and B. malayi in endemic areas of Peninsular Malaysia. In the microfilaria-negative group, without signs and symptoms of filariasis 55/62 sera (89%) had titers of 1:16 and less. In the microfilaremic groups and in the amicrofilaremic cases with clinical filariasis, all the sera tested were positive, with the antibody titers ranging generally from 1:16 - 1:256. Cross-reaction tests were done on 16 samples of onchocerciasis sera from West Africa using sonicated antigen as well as antigen-coated CNB1-activated sepharose. Antibody titers were detected in all the sera. The usefulness of the sonicated microfilarial antigen in serodiagnosis of filariasis is discussed.||Source Title:||Southeast Asian Journal of Tropical Medicine and Public Health||URI:||http://scholarbank.nus.edu.sg/handle/10635/133644||ISSN:||00383619|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jun 20, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.