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|Title:||HLA and leprosy in Chinese||Authors:||Chan, S.H.
|Issue Date:||1979||Citation:||Chan, S.H., Oon, B.B., Kamarudin, A., Wee, G.B. (1979). HLA and leprosy in Chinese. Tissue Antigens 13 (1) : 73-74. ScholarBank@NUS Repository.||Abstract:||The authors have studied 77 unrelated Chinese leprosy patients; 40 lepromatous (LL) and 37 tuberculoid (TT and BT). The control group consisted of 238 unrelated normal Chinese subjects. The frequency of HLA-B17 was higher among the leprosy patients as a group than among controls. Twenty-three (29.9% of 77 leprosy patients had B17 compared with 34 of 238 (14.3%) controls. This difference was not significant when corrected for the 26 antigens typed for. The high frequency of B17 was particularly marked in the patient subgroup of tuberculoid leprosy. Fifteen (40.5%) of 37 tuberculoid leprosy patients had B17 compared with 34 of 238 (14.3%) controls. This difference was significant even after corrected for the number of antigens typed for. Lepromatous leprosy patients had a higher frequency of B13 and a lower frequency of A2 than tuberculoid leprosy patients or controls but these differences were not statistically significant.||Source Title:||Tissue Antigens||URI:||http://scholarbank.nus.edu.sg/handle/10635/133233||ISSN:||00012815|
|Appears in Collections:||Staff Publications|
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