Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/133233
Title: HLA and leprosy in Chinese
Authors: Chan, S.H. 
Oon, B.B.
Kamarudin, A.
Wee, G.B.
Issue Date: 1979
Citation: Chan, S.H., Oon, B.B., Kamarudin, A., Wee, G.B. (1979). HLA and leprosy in Chinese. Tissue Antigens 13 (1) : 73-74. ScholarBank@NUS Repository.
Abstract: The authors have studied 77 unrelated Chinese leprosy patients; 40 lepromatous (LL) and 37 tuberculoid (TT and BT). The control group consisted of 238 unrelated normal Chinese subjects. The frequency of HLA-B17 was higher among the leprosy patients as a group than among controls. Twenty-three (29.9% of 77 leprosy patients had B17 compared with 34 of 238 (14.3%) controls. This difference was not significant when corrected for the 26 antigens typed for. The high frequency of B17 was particularly marked in the patient subgroup of tuberculoid leprosy. Fifteen (40.5%) of 37 tuberculoid leprosy patients had B17 compared with 34 of 238 (14.3%) controls. This difference was significant even after corrected for the number of antigens typed for. Lepromatous leprosy patients had a higher frequency of B13 and a lower frequency of A2 than tuberculoid leprosy patients or controls but these differences were not statistically significant.
Source Title: Tissue Antigens
URI: http://scholarbank.nus.edu.sg/handle/10635/133233
ISSN: 00012815
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

20
checked on Aug 16, 2019

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.