Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/133073
DC FieldValue
dc.titleNeural progenitor and stem cells in the adult central nervous system
dc.contributor.authorTaupin, P.
dc.date.accessioned2016-12-13T05:39:54Z
dc.date.available2016-12-13T05:39:54Z
dc.date.issued2006-11
dc.identifier.citationTaupin, P. (2006-11). Neural progenitor and stem cells in the adult central nervous system. Annals of the Academy of Medicine Singapore 35 (11) : 814-820. ScholarBank@NUS Repository.
dc.identifier.issn03044602
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/133073
dc.description.abstractNeurogenesis occurs in the adult brain, and neural stem cells (NSCs) reside in the adult central nervous system (CNS). In the adult brain, newly generated neuronal cells would originate from a population of glial cells with stem cells properties, and be involved in processes such as learning and memory, depression, and in regenerative attempts in the diseased brain and after injuries. In human, a recent study reported no evidence of migrating neural progenitor cells along the subventricular zone (SVZ) to the olfactory bulb (OB), contrary to other species, highlighting the particularity of adult neurogenesis in human. Though the origin and contribution of newly generated neuronal cells to CNS pathophysiology remain to be fully understood, the discovery that NSCs reside in the adult CNS force us to re-evaluate our knowledge and understanding of brain functioning, and suggest that the adult CNS may be amenable to repair. In this manuscript, we will review the recent data, debates and controversies on the identification, origin and function of newly generated neuronal cells in the adult brain, in human and in other species. We will discuss their contribution and significance to CNS pathophysiology, and for cellular therapy.
dc.sourceScopus
dc.subjectHippocampus
dc.subjectNeuronal Plasticity
dc.subjectPhysiopathology
dc.subjectRegeneration
dc.subjectTherapy
dc.typeReview
dc.contributor.departmentOBSTETRICS & GYNAECOLOGY
dc.description.sourcetitleAnnals of the Academy of Medicine Singapore
dc.description.volume35
dc.description.issue11
dc.description.page814-820
dc.description.codenAAMSC
dc.identifier.isiutNOT_IN_WOS
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

Page view(s)

22
checked on Nov 28, 2020

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.