Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/132700
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dc.titleMitogenic capacity of oxidized human B cell lines
dc.contributor.authorRen, E.C.
dc.contributor.authorChan, S.H.
dc.date.accessioned2016-12-13T05:35:29Z
dc.date.available2016-12-13T05:35:29Z
dc.date.issued1984
dc.identifier.citationRen, E.C., Chan, S.H. (1984). Mitogenic capacity of oxidized human B cell lines. European Journal of Immunology 14 (12) : 1156-1158. ScholarBank@NUS Repository.
dc.identifier.issn00142980
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/132700
dc.description.abstractA combination of neuraminidase and galactose oxidase alters the membrane glycoproteins to generate highly reactive aldehyde groups on galactose moieties. Human B cell lines oxidized in this way were able to induce strong proliferative responses from normal untreated peripheral blood lymphocytes. Oxidized cell lines that stimulate well were also correlated to some extent with their ability to bind responder lymphocytes. The present investigation demonstrates the usefulness of oxidized B cell lines as a novel mitogen for use in the study of lymphocyte activation.
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentWHO IMMUNOLOGY RESEARCH & TRAINING CTR
dc.description.sourcetitleEuropean Journal of Immunology
dc.description.volume14
dc.description.issue12
dc.description.page1156-1158
dc.description.codenEJIMA
dc.identifier.isiutNOT_IN_WOS
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