Please use this identifier to cite or link to this item: https://doi.org/10.1097/00003226-200401000-00011
DC FieldValue
dc.titleExpression of p63 in Pterygium and Normal Conjunctiva
dc.contributor.authorSakoonwatanyoo, P.
dc.contributor.authorTan, D.T.H.
dc.contributor.authorSmith, D.R.
dc.date.accessioned2016-12-13T05:34:24Z
dc.date.available2016-12-13T05:34:24Z
dc.date.issued2004-01
dc.identifier.citationSakoonwatanyoo, P., Tan, D.T.H., Smith, D.R. (2004-01). Expression of p63 in Pterygium and Normal Conjunctiva. Cornea 23 (1) : 67-70. ScholarBank@NUS Repository. https://doi.org/10.1097/00003226-200401000-00011
dc.identifier.issn02773740
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/132604
dc.description.abstractPurpose: The p63 gene has been identified as a marker of epithelial stem cells. Because pterygium may arise through an expansion of the proliferative capacity of the conjunctiva, we sought to document the expression of p63 in normal conjunctiva and pterygium specimens. Methods: Immunostaining for p63 expression was performed on 10 pairs of pterygium and normal conjunctiva using a monoclonal antibody directed against human p63. Results: Immunopositive reactions were seen in all samples. Levels of p63-positive cells were not statistically different between pterygium and normal conjunctivae (P = 0.7). Conclusion: These results strongly support previous studies that indicate that pterygium arises as a result of incorrect control of cellular apoptosis rather than from an increase in proliferative capacity.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1097/00003226-200401000-00011
dc.sourceScopus
dc.subjectApoptosis
dc.subjectp63
dc.subjectProliferation
dc.subjectPterygium
dc.typeArticle
dc.contributor.departmentOPHTHALMOLOGY
dc.description.doi10.1097/00003226-200401000-00011
dc.description.sourcetitleCornea
dc.description.volume23
dc.description.issue1
dc.description.page67-70
dc.description.codenCORND
dc.identifier.isiut000189192000011
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.