Please use this identifier to cite or link to this item: https://doi.org/10.1007/s11068-009-9039-x
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dc.titleImaging activity of neuronal populations with new long-wavelength voltage-sensitive dyes
dc.contributor.authorKee, M.Z.L.
dc.contributor.authorWuskell, J.P.
dc.contributor.authorLoew, L.M.
dc.contributor.authorAugustine, G.J.
dc.contributor.authorSekino, Y.
dc.date.accessioned2016-12-13T05:33:02Z
dc.date.available2016-12-13T05:33:02Z
dc.date.issued2008-12
dc.identifier.citationKee, M.Z.L., Wuskell, J.P., Loew, L.M., Augustine, G.J., Sekino, Y. (2008-12). Imaging activity of neuronal populations with new long-wavelength voltage-sensitive dyes. Brain Cell Biology 36 (5-6) : 157-172. ScholarBank@NUS Repository. https://doi.org/10.1007/s11068-009-9039-x
dc.identifier.issn15597105
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/132489
dc.description.abstractWe have assessed the utility of five new long-wavelength fluorescent voltage-sensitive dyes (VSD) for imaging the activity of populations of neurons in mouse brain slices. Although all the five were capable of detecting activity resulting from activation of the Schaffer collateral-CA1 pyramidal cell synapse, they differed significantly in their properties, most notably in the signal-to-noise ratio of the changes in dye fluorescence associated with neuronal activity. Two of these dyes, Di-2-ANBDQPQ and Di-1-APEFEQPQ, should prove particularly useful for imaging activity in brain tissue and for combining VSD imaging with the control of neuronal activity via light-activated proteins such as channelrhodopsin-2 and halorhodopsin. © 2009 Springer Science+Business Media, LLC.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1007/s11068-009-9039-x
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentDUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE
dc.description.doi10.1007/s11068-009-9039-x
dc.description.sourcetitleBrain Cell Biology
dc.description.volume36
dc.description.issue5-6
dc.description.page157-172
dc.identifier.isiut000264514300001
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