Please use this identifier to cite or link to this item:
|Title:||Serum antibodies to Trichomonas vaginalis in invasive cervical cancer patients||Authors:||Yap, E.H.
|Issue Date:||1995||Citation:||Yap, E.H., Ho, T.H., Chan, Y.C., Thong, T.W., Ng, G.C., Mo, L.C., Singh, M. (1995). Serum antibodies to Trichomonas vaginalis in invasive cervical cancer patients. Genitourinary Medicine 71 (6) : 402-404. ScholarBank@NUS Repository.||Abstract:||Objective - To evaluate, by seroepidemiology, the possible role of the sexually-transmitted flagellate, Trichomonas vaginalis, in invasive cervical cancer. Subjects and method - Sera from 121 invasive cervical cancer patients and 242 random age-matched female controls. Antibodies to T. vaginalis were detected by the western blot technique. Results - Antibodies to T. vaginalis were detected in the sera of 41.3% (50/121) of invasive cervical cancer patients compared with only 5.0% (12/242) of female controls. All the reactive sera reacted strongly with the immunogenic surface membrane proteins of T. vaginalis of molecular weights of about 92 and 115 kDa, with variable reactivity to other immunogenic proteins of T. vaginalis. Conclusion - The significantly increased relative risk, RR = 3.42 (95% CI = 1.73-6.78), is comparable to the RRs derived in seroepidemiological studies of human papillomavirus, suggesting that T. vaginalis may be even more closely associated with invasive cervical cancer than previously realized.||Source Title:||Genitourinary Medicine||URI:||http://scholarbank.nus.edu.sg/handle/10635/132021||ISSN:||02664348|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Oct 11, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.