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Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/131418
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dc.titleHuman leucocyte antigen DNA typing in Singaporean Chinese patients with Graves' disease.
dc.contributor.authorChan, S.H.
dc.contributor.authorLin, Y.N.
dc.contributor.authorWee, G.B.
dc.contributor.authorRen, E.C.
dc.contributor.authorLui, K.F.
dc.contributor.authorCheah, J.S.
dc.date.accessioned2016-11-28T10:19:59Z
dc.date.available2016-11-28T10:19:59Z
dc.date.issued1993-07
dc.identifier.citationChan, S.H., Lin, Y.N., Wee, G.B., Ren, E.C., Lui, K.F., Cheah, J.S. (1993-07). Human leucocyte antigen DNA typing in Singaporean Chinese patients with Graves' disease.. Annals of the Academy of Medicine Singapore 22 (4) : 576-579. ScholarBank@NUS Repository.
dc.identifier.issn03044602
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/131418
dc.description.abstractHuman Leucocyte Antigen (HLA) A, B, C, DR, DQ and DP locus alleles in 35 Chinese patients with Graves' disease and 80 controls were typed for using serological and DNA polymerase chain reaction/sequence specific oligonucleotide (PCR/SSO) methods. B46 was found to be strongly associated with male patients (p = 0.0002; RR = 8.2, 95% confidence interval 2.1-32.2). In HLA class 1 alleles, besides B46, the frequencies of A2 and Cw1 were increased and A24 and B63 decreased in patients compared to controls. In HLA class 2 alleles, the frequencies of DRB1*1602, *0301, *1405, DRB5*02, DQB1*0502 were increased and DRB1*1501, DQB1*0301 decreased in patients.
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentWHO IMMUNOLOGY RESEARCH & TRAINING CTR
dc.contributor.departmentMICROBIOLOGY
dc.contributor.departmentMEDICINE
dc.description.sourcetitleAnnals of the Academy of Medicine Singapore
dc.description.volume22
dc.description.issue4
dc.description.page576-579
dc.identifier.isiutNOT_IN_WOS
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