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Title: High prevalence of dyslipidaemia despite adequate glycaemic control in patients with diabetes
Authors: Loh, K.C.
Thai, A.C. 
Lui, K.F.
Ng, W.Y. 
Keywords: Cholesterol
Glycated haemoglobin
High-density lipoprotein (HDL)
Low-density lipoprotein (LDL)
Very low-density lipoprotein (VLDL)
Issue Date: Mar-1996
Citation: Loh, K.C., Thai, A.C., Lui, K.F., Ng, W.Y. (1996-03). High prevalence of dyslipidaemia despite adequate glycaemic control in patients with diabetes. Annals of the Academy of Medicine Singapore 25 (2) : 228-232. ScholarBank@NUS Repository.
Abstract: Forty-seven patients with newly diagnosed diabetes were followed up for 1 year with lipid parameters (total cholesterol, low-density lipoprotein [LDL] cholesterol, high-density lipoprotein [HDL] cholesterol and triglycerides) and glycated haemoglobin measured at diagnosis and 6-monthly intervals. The prevalence of these lipid parameters exceeding the risk level for coronary heart disease at diagnosis ranged from 34% to 64%, the commonest dyslipidaemic pattern being hypercholesterolaemia (43%), followed by mixed hyperlipidaemia (17%) and hypertriglyceridaemia (17%). There was no improvement in the lipids profile over a 1-year period despite achieving good glycaemic control in both the insulin-dependent diabetes mellitus (IDDM) and non-insulin-dependent diabetes mellitus (NIDDM) patients. Twenty-four (51%) patients will need lipid lowering treatment because of persistent dyslipidaemia despite adequate non-pharmacologic measures. We suggest that an active strategy of early detection and drug treatment for dyslipidaemia is needed for patients with diabetes mellitus.
Source Title: Annals of the Academy of Medicine Singapore
ISSN: 03044602
Appears in Collections:Staff Publications

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