Effects of lens opacity on AccuMap multifocal objective perimetry in glaucoma

Abstract

Objective: To investigate the effect of lens opacity on the performance of the multi-focal visual evoked potential (mfVEP) test in patients with glaucoma and its relationship with the Humphrey's automated static perimetry. Methods: This is a prospective, non-randomized study. Twenty-two patients were enrolled with moderate cataract and primary glaucoma scheduled for cataract surgery with or without glaucoma surgery. Humphrey visual field and mfVEP test were preformed before surgery and after 6-8 weeks of post-operation. Lens opacity was evaluated with slit lamp according to LOCS III (lens opacity classification system, version III) by the same ophthalmologist. Results: The improvement of AccuMap objective visual field was noted after lens removal in glaucoma patients. The amplitude of the AccuMap was significantly (P < 0.01) increased after cataract surgery compared to pre-operation (382.6 nV ±146.7 nV vs 308.0 nV ± 96.6 nV). AccuMap severity index (ASI) was significantly (P < 0.001 decreased following lens removal compared with pre-operation (48.6±42.4 vs 90.0±54.8, P