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Title: Acute lung injury after inhalation of nitric acid
Authors: Kao, S.L.
Yap, E.S.
Khoo, S.M.
Lim, T.K. 
Mukhopadhyay, A.
Teo, S.T.L.
Keywords: Acute lung injury
Inhalation injury
Nitric acid
Issue Date: Dec-2008
Citation: Kao, S.L., Yap, E.S., Khoo, S.M., Lim, T.K., Mukhopadhyay, A., Teo, S.T.L. (2008-12). Acute lung injury after inhalation of nitric acid. European Journal of Emergency Medicine 15 (6) : 348-350. ScholarBank@NUS Repository.
Abstract: We report two cases of acute lung injury after the inhalation of nitric acid fumes in an industrial accident. The first patient, who was not using a respirator and standing in close proximity to the site of spillage of concentrated nitric acid, presented within 12 h with worsening dyspnea and required noninvasive ventilation for type 1 respiratory failure. The second case presented 1 day later with similar symptoms, but only required supportive treatment with high-flow oxygen. Both patients' chest radiographs showed widespread bilateral airspace shadows consistent with acute lung injury. Both received treatment with systemic steroids. They were discharged from hospital 5 days postexposure. Initial lung function test showed a restrictive pattern that normalized by 3 weeks postexposure. This case series describes the natural history after acute inhalation of nitric acid fumes, and demonstrates that the severity of lung injury is directly dependent on the exposure level. It also highlights the use of noninvasive ventilatory support in the management of such patients. European Journal of Emergency Medicine 15:348-350. © 2008 Wolters Kluwer Health.
Source Title: European Journal of Emergency Medicine
ISSN: 09699546
DOI: 10.1097/MEJ.0b013e3282f542ea
Appears in Collections:Staff Publications

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