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Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.jgg.2014.03.003
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dc.titleRecent advances in understanding proteins involved in lipid droplet formation, growth and fusion
dc.contributor.authorTan, J.S.Y.
dc.contributor.authorSeow, C.J.P.
dc.contributor.authorGoh, V.J.
dc.contributor.authorSilver, D.L.
dc.date.accessioned2016-10-19T08:43:44Z
dc.date.available2016-10-19T08:43:44Z
dc.date.issued2014-05-20
dc.identifier.citationTan, J.S.Y., Seow, C.J.P., Goh, V.J., Silver, D.L. (2014-05-20). Recent advances in understanding proteins involved in lipid droplet formation, growth and fusion. Journal of Genetics and Genomics 41 (5) : 251-259. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jgg.2014.03.003
dc.identifier.issn18735533
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/128660
dc.description.abstractLipid droplets (LDs) were once viewed as simple, inert lipid micelles. However, they are now known to be organelles with a rich proteome involved in a myriad of cellular processes. LDs are heterogeneous in nature with different sizes and compositions of phospholipids, neutral lipids and proteins. This review takes a focused look at the roles of proteins involved in the regulation of LD formation, expansion, and morphology. The related proteins are summarized such as the fat-specific protein (Fsp27), fat storage-inducing transmembrane (FIT) proteins, seipin and ADP-ribosylation factor 1-coat protein complex I (Arf-COPI). Finally, we present important challenges in LD biology for a deeper understanding of this dynamic organelle to be achieved. © 2014.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.jgg.2014.03.003
dc.sourceScopus
dc.subjectLD-associated proteins
dc.subjectLipid droplets
dc.subjectPerilipin
dc.subjectPhospholipids
dc.typeReview
dc.contributor.departmentDUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE
dc.description.doi10.1016/j.jgg.2014.03.003
dc.description.sourcetitleJournal of Genetics and Genomics
dc.description.volume41
dc.description.issue5
dc.description.page251-259
dc.identifier.isiut000337273200003
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