Please use this identifier to cite or link to this item: https://doi.org/10.1099/jmm.0.022533-0
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dc.titleSix cases of daptomycin-non-susceptible Staphylococcus aureus bacteraemia in Singapore
dc.contributor.authorHsu, L.-Y.
dc.contributor.authorLeong, M.
dc.contributor.authorBalm, M.
dc.contributor.authorChan, D.S.
dc.contributor.authorHuggan, P.
dc.contributor.authorTan, T.-Y.
dc.contributor.authorKoh, T.-H.
dc.contributor.authorHon, P.-Y.
dc.contributor.authorNg, M.M.
dc.date.accessioned2016-09-07T08:58:40Z
dc.date.available2016-09-07T08:58:40Z
dc.date.issued2010-12
dc.identifier.citationHsu, L.-Y., Leong, M., Balm, M., Chan, D.S., Huggan, P., Tan, T.-Y., Koh, T.-H., Hon, P.-Y., Ng, M.M. (2010-12). Six cases of daptomycin-non-susceptible Staphylococcus aureus bacteraemia in Singapore. Journal of Medical Microbiology 59 (12) : 1509-1513. ScholarBank@NUS Repository. https://doi.org/10.1099/jmm.0.022533-0
dc.identifier.issn00222615
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/127124
dc.description.abstractWe report what we believe to be the first six cases of daptomycin-non- susceptible Staphylococcus aureus infections from Singapore. These strains were rapidly isolated after bacteraemic patients were switched to daptomycin following initial prolonged unsuccessful therapy with vancomycin, despite confirmation of daptomycin susceptibility just prior to initiating daptomycin therapy. The majority of post-vancomycin therapy strains exhibited marked thickening of their cell walls on electron microscopic examination. In patients with persistent S. aureus bacteraemia, therapeutic failure with daptomycin may occur if used as salvage therapy following vancomycin failure, notwithstanding initial susceptibility testing results. © 2010 SGM.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1099/jmm.0.022533-0
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentMEDICINE
dc.contributor.departmentMICROBIOLOGY
dc.description.doi10.1099/jmm.0.022533-0
dc.description.sourcetitleJournal of Medical Microbiology
dc.description.volume59
dc.description.issue12
dc.description.page1509-1513
dc.description.codenJMMIA
dc.identifier.isiut000285271900015
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