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Title: Mediastinal re-staging of non small-cell lung cancer
Authors: Khoo, K.-L. 
Keywords: Endobronchial ultrasound
Endoscopic ultrasound
Non small cell lung cancer
Transbronchial needle aspiration
Issue Date: May-2012
Citation: Khoo, K.-L. (2012-05). Mediastinal re-staging of non small-cell lung cancer. Thoracic Cancer 3 (2) : 145-149. ScholarBank@NUS Repository.
Abstract: Selected patients with non small-cell lung cancer (NSCLC) with mediastinal lymph node involvement may have a survival benefit from surgical resection, particularly if mediastinal nodal down-staging occurs after induction therapy and complete resection is achieved with lobectomy. Accurate re-staging of the mediastinum after induction therapy is therefore crucial in determining prognosis and subsequent treatment. Non-invasive imaging techniques usually require a confirmatory tissue sampling method to improve the accuracy of mediastinal re-staging.As in the initial staging of the mediastinum, minimally invasive endosonography-guided needle sampling techniques such as endobronchial ultrasound-guided fine-needle aspiration (EBUS-TBNA) and endoscopic ultrasound-guided fine-needle aspiration show promise in re-staging the mediastinum, though invasive surgical re-staging remains the gold standard. Despite a lower sensitivity in the mediastinal re-staging of NSCLC, EBUS-TBNA with or without EUS-FNA may still be the preferred initial mediastinal re-staging technique. © 2011 Tianjin Lung Cancer Institute and Blackwell Publishing Asia Pty. Ltd.
Source Title: Thoracic Cancer
ISSN: 17597706
DOI: 10.1111/j.1759-7714.2011.00097.x
Appears in Collections:Staff Publications

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