Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0929-6646(10)60102-7
Title: Fluoroquinolone Prophylaxis Against Febrile Neutropenia in Areas With High Fluoroquinolone Resistance-An Asian Perspective
Authors: Ng, E.S.T.
Liew, Y.
Koh, L.P.
Hsu, L.Y. 
Keywords: Antimicrobial resistance
Asia
Febrile neutropenia
Fluoroquinolone
Prophylaxis
Issue Date: 2010
Citation: Ng, E.S.T., Liew, Y., Koh, L.P., Hsu, L.Y. (2010). Fluoroquinolone Prophylaxis Against Febrile Neutropenia in Areas With High Fluoroquinolone Resistance-An Asian Perspective. Journal of the Formosan Medical Association 109 (9) : 624-631. ScholarBank@NUS Repository. https://doi.org/10.1016/S0929-6646(10)60102-7
Abstract: Febrile neutropenia remains a major cause of morbidity and mortality in patients receiving chemotherapy. Major prophylactic strategies include granulocyte colony-stimulating factor and antibiotics, the most widely used of which are fluoroquinolones. While fluoroquinolone prophylaxis has been shown to be effective in areas where fluoroquinolone resistance is low, this same efficacy has not been proven in areas where resistance is high, such as in Asia. Given the increase in antimicrobial resistance with the use of prophylaxis, the risks and benefits of this strategy need to be carefully considered. This review presents the evidence for and against fluoroquinolone prophylaxis in areas of high fluoroquinolone resistance. © 2010 Formosan Medical Association & Elsevier.
Source Title: Journal of the Formosan Medical Association
URI: http://scholarbank.nus.edu.sg/handle/10635/126923
ISSN: 09296646
DOI: 10.1016/S0929-6646(10)60102-7
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