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Title: Antiganglioside antibodies in Guillain-Barré syndrome and its related conditions
Authors: Shahrizaila, N.
Yuki, N. 
Keywords: antiganglioside antibodies
Fisher syndrome
Guillain-Barré syndrome
Issue Date: Sep-2011
Citation: Shahrizaila, N., Yuki, N. (2011-09). Antiganglioside antibodies in Guillain-Barré syndrome and its related conditions. Expert Review of Neurotherapeutics 11 (9) : 1305-1313. ScholarBank@NUS Repository.
Abstract: Guillain-Barré syndrome (GBS) is typically classified into two major subtypes: acute inflammatory demyelinating neuropathy and acute motor axonal neuropathy. Its most recognizable variant is Fisher syndrome. The last two decades have seen considerable advances in our understanding of GBS. Of note, various autoantibodies against ganglioside antigens have been identified and found to have significant associations with the axonal forms of GBS and Fisher syndrome. In this article, we discuss the different clinical presentations in GBS and the role of antiganglioside antibodies in their underlying pathogenesis. We also discuss the impact that antiganglioside antibodies have had in the development of experimental models and treatment modalities in GBS. © 2011 Expert Reviews Ltd.
Source Title: Expert Review of Neurotherapeutics
ISSN: 14737175
DOI: 10.1586/ern.11.114
Appears in Collections:Staff Publications

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