Please use this identifier to cite or link to this item: https://doi.org/10.1097/JCP.0b013e3182726623
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dc.titleCommon use of antipsychotic polypharmacy in older asian patients with schizophrenia (2001-2009)
dc.contributor.authorXiang, Y.-T.
dc.contributor.authorDickerson, F.
dc.contributor.authorKreyenbuhl, J.
dc.contributor.authorUngvari, G.S.
dc.contributor.authorWang, C.-Y.
dc.contributor.authorSi, T.-M.
dc.contributor.authorLee, E.H.M.
dc.contributor.authorHe, Y.-L.
dc.contributor.authorChiu, H.F.K.
dc.contributor.authorYang, S.-Y.
dc.contributor.authorChong, M.-Y.
dc.contributor.authorTan, C.-H.
dc.contributor.authorKua, E.-H.
dc.contributor.authorFujii, S.
dc.contributor.authorSim, K.
dc.contributor.authorYong, M.K.H.
dc.contributor.authorTrivedi, J.K.
dc.contributor.authorChung, E.-K.
dc.contributor.authorUdomratn, P.
dc.contributor.authorChee, K.-Y.
dc.contributor.authorSartorius, N.
dc.contributor.authorShinfuku, N.
dc.date.accessioned2016-07-10T02:36:50Z
dc.date.available2016-07-10T02:36:50Z
dc.date.issued2012-12
dc.identifier.citationXiang, Y.-T., Dickerson, F., Kreyenbuhl, J., Ungvari, G.S., Wang, C.-Y., Si, T.-M., Lee, E.H.M., He, Y.-L., Chiu, H.F.K., Yang, S.-Y., Chong, M.-Y., Tan, C.-H., Kua, E.-H., Fujii, S., Sim, K., Yong, M.K.H., Trivedi, J.K., Chung, E.-K., Udomratn, P., Chee, K.-Y., Sartorius, N., Shinfuku, N. (2012-12). Common use of antipsychotic polypharmacy in older asian patients with schizophrenia (2001-2009). Journal of Clinical Psychopharmacology 32 (6) : 809-813. ScholarBank@NUS Repository. https://doi.org/10.1097/JCP.0b013e3182726623
dc.identifier.issn02710749
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/125898
dc.description.abstractOBJECTIVE: The aim of this study was to survey the use of antipsychotic polypharmacy (APP) in older Asian patients with schizophrenia and examine its demographic and clinical correlates. METHODS: Information on hospitalized patients with schizophrenia aged 55 or older was extracted from the database of the Research on Asian Psychotropic Prescription Patterns study. Data on 1439 patients in 6 Asian countries and territories including China, Hong Kong, Japan, Korea, Singapore, and Taiwan were analyzed. Sociodemographic and clinical characteristics and antipsychotic prescriptions were recorded using a standardized protocol and data collection procedure. RESULTS: The frequency of APP prescription was 51.6% in the pooled sample with wide intercountry variations. Multiple logistic regression analysis of the whole sample showed that patients on APP had higher antipsychotic doses and also were more likely to receive first-generation antipsychotics. CONCLUSIONS: Use of APP was common in older Asian patients with schizophrenia. Given the limited evidence supporting its efficacy, the potentially severe side effects and high costs, APP should be used with caution in this population. The reasons for and outcomes of the use of APP in this patient population merit further exploration. Copyright © 2012 Lippincott Williams & Wilkins.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1097/JCP.0b013e3182726623
dc.sourceScopus
dc.subjectantipsychotic polypharmacy
dc.subjectAsia
dc.subjectprescription patterns
dc.subjectpsychogeriatric patients
dc.subjectschizophrenia
dc.typeReview
dc.contributor.departmentPHARMACOLOGY
dc.contributor.departmentPSYCHOLOGICAL MEDICINE
dc.description.doi10.1097/JCP.0b013e3182726623
dc.description.sourcetitleJournal of Clinical Psychopharmacology
dc.description.volume32
dc.description.issue6
dc.description.page809-813
dc.description.codenJCPYD
dc.identifier.isiut000310923500013
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