Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.jocn.2011.02.030
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dc.titleThe clinico-radiological spectrum of isolated cortical vein thrombosis
dc.contributor.authorRathakrishnan, R.
dc.contributor.authorSharma, V.K.
dc.contributor.authorLuen, T.H.
dc.contributor.authorChan, B.P.L.
dc.date.accessioned2016-07-10T02:36:25Z
dc.date.available2016-07-10T02:36:25Z
dc.date.issued2011-10
dc.identifier.citationRathakrishnan, R., Sharma, V.K., Luen, T.H., Chan, B.P.L. (2011-10). The clinico-radiological spectrum of isolated cortical vein thrombosis. Journal of Clinical Neuroscience 18 (10) : 1408-1411. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jocn.2011.02.030
dc.identifier.issn09675868
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/125865
dc.description.abstractIsolated cortical vein thrombosis (ICVT) in the absence of sinus or great venous involvement is rare. Various MRI sequences have been proposed for diagnostic accuracy, although follow-up data are limited. The optimal management strategy remains uncertain. Patients with ICVT treated between 2006 and 2008 were retrospectively studied. Diagnostic and follow-up neuroimaging were reviewed independently, and we evaluated their treatment and outcomes. Five patients (mean age 41 years; range, 25-54 years) were included. All presented with seizures. Focal neurological deficits were noted in one patient only. T2 susceptibility-weighted MRI abnormalities were observed in all patients. T2-weighted parenchymal hyperintensities involving the cortical-subcortical regions around the ICVT had completely resolved on follow-up scans. Clinical outcomes were uniformly good, despite variable treatment strategies. We observed significant, yet reversible, parenchymal T2-weighted MRI lesions in our patients with ICVT. Follow-up clinical and radiological studies demonstrate recovery independent of treatment regimes. T2-weighted MRI was found to be a useful diagnostic tool and might improve diagnostic accuracy in carefully selected patients with new-onset seizures. © 2011 Elsevier Masson SAS. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.jocn.2011.02.030
dc.sourceScopus
dc.subjectAnticoagulation
dc.subjectCortical vein thrombosis
dc.subjectMRI
dc.subjectSeizures
dc.typeReview
dc.contributor.departmentMEDICINE
dc.description.doi10.1016/j.jocn.2011.02.030
dc.description.sourcetitleJournal of Clinical Neuroscience
dc.description.volume18
dc.description.issue10
dc.description.page1408-1411
dc.description.codenJCNUE
dc.identifier.isiut000295188900030
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