Please use this identifier to cite or link to this item: https://doi.org/10.1038/nn.3423
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dc.titleOpportunities and limitations of intrinsic functional connectivity MRI
dc.contributor.authorBuckner, R.L.
dc.contributor.authorKrienen, F.M.
dc.contributor.authorYeo, B.T.T.
dc.date.accessioned2016-06-01T10:32:52Z
dc.date.available2016-06-01T10:32:52Z
dc.date.issued2013-07
dc.identifier.citationBuckner, R.L., Krienen, F.M., Yeo, B.T.T. (2013-07). Opportunities and limitations of intrinsic functional connectivity MRI. Nature Neuroscience 16 (7) : 832-837. ScholarBank@NUS Repository. https://doi.org/10.1038/nn.3423
dc.identifier.issn10976256
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/124878
dc.description.abstractIntrinsic functional connectivity magnetic resonance imaging (fcMRI) has emerged as a powerful tool for mapping large-scale networks in the human brain. Robust and reliable functionally coupled networks can be detected in individuals that echo many known features of anatomical organization. Features of brain organization have been discovered, including descriptions of distributed large-scale networks interwoven throughout association cortex, interactions (including anticorrelations) between brain networks and insights into the topography of subcortical structures. But interpreting fcMRI is complicated by several factors. Functional coupling changes dynamically, suggesting that it is constrained by, but not fully dictated by, anatomic connectivity. Critically to study of between-group differences, fcMRI is sensitive to head motion and to differences in the mental states of participants during the scans. We discuss the potential of fcMRI in the context of its limitations. © 2013 Nature America, Inc. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1038/nn.3423
dc.sourceScopus
dc.typeReview
dc.contributor.departmentDUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE
dc.description.doi10.1038/nn.3423
dc.description.sourcetitleNature Neuroscience
dc.description.volume16
dc.description.issue7
dc.description.page832-837
dc.description.codenNANEF
dc.identifier.isiut000321180900013
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