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Title: Hepatic adenoma mimicking a metastatic lesion on computed tomography-positron emission tomography scan
Authors: Lim, D.
Lee, S.Y. 
Lim, K.H. 
Chan, C.Y. 
Keywords: 18F-fluorodeoxyglucose
Hepatic adenoma
Hepatocellular adenoma
Hepatocyte nuclear factor-1 α
Positron emission tomography
Issue Date: 2013
Citation: Lim, D., Lee, S.Y., Lim, K.H., Chan, C.Y. (2013). Hepatic adenoma mimicking a metastatic lesion on computed tomography-positron emission tomography scan. World Journal of Gastroenterology 19 (27) : 4432-4436. ScholarBank@NUS Repository.
Abstract: Positron emission tomography (PET) using 18F-fluorodeoxyglucose (18F-FDG) is an imaging modality which reflects cellular glucose metabolism. Most malignant cells accumulate and trap 18F-FDG, allowing the visualisation of increased uptake. It is hence widely used to differentiate malignant from benign lesions. "False positive" findings of hepatic lesions have been described in certain instances such as hepatic abscesses, but are rare in cases involving hepatocellular adenomas. To our knowledge, there have been only 7 reports in the English literature documenting PET-avid hepatocellular adenomas; 6 of the 7 reports were published in the last 3 years with the first report by Patel et al. We report the case of a 44-year-old Chinese female patient with a history of cervical adenocarcinoma, referred for a hepatic lesion noted on a surveillance computed tomography (CT) scan. A subsequent CT-PET performed showed a hypermetabolic lesion (standardized uptake value 7.9) in segment IVb of the liver. After discussion at a multidisciplinary hepato-pancreato-biliary conference, the consensus was that of a metastatic lesion from her previous cervical adenocarcinoma, and a resection of the hepatic lesion was performed. Histology revealed features consistent with a hepatocyte nuclear factor-1 α inactivated steatotic hepatocellular adenoma. © 2013 Baishideng. All rights reserved.
Source Title: World Journal of Gastroenterology
ISSN: 10079327
DOI: 10.3748/wjg.v19.i27.4432
Appears in Collections:Staff Publications

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