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Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.bmcl.2007.08.078
DC FieldValue
dc.titleSynthesis, characterization and evaluation of benzimidazole derivative and its precursors as inhibitors of MDA-MB-231 human breast cancer cell proliferation
dc.contributor.authorThimmegowda, N.R.
dc.contributor.authorNanjunda Swamy, S.
dc.contributor.authorAnanda Kumar, C.S.
dc.contributor.authorSunil Kumar, Y.C.
dc.contributor.authorChandrappa, S.
dc.contributor.authorYip, G.W.
dc.contributor.authorRangappa, K.S.
dc.date.accessioned2015-09-07T09:55:31Z
dc.date.available2015-09-07T09:55:31Z
dc.date.issued2008-01-01
dc.identifier.citationThimmegowda, N.R., Nanjunda Swamy, S., Ananda Kumar, C.S., Sunil Kumar, Y.C., Chandrappa, S., Yip, G.W., Rangappa, K.S. (2008-01-01). Synthesis, characterization and evaluation of benzimidazole derivative and its precursors as inhibitors of MDA-MB-231 human breast cancer cell proliferation. Bioorganic and Medicinal Chemistry Letters 18 (1) : 432-435. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bmcl.2007.08.078
dc.identifier.issn0960894X
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/120673
dc.description.abstractA novel series of trisubstituted benzimidazole and its precursors (3-7) were synthesised and characterized by using 1H NMR, LC/MS, FTIR and elemental analysis techniques. The title compounds were evaluated for inhibition against MDA-MB-231 breast cancer cell proliferation. The results revealed that the compound N-(4-cyano-3-(trifluoromethyl) phenyl)-4-fluoro-3-nitrobenzamide (3) was the potent inhibitor. © 2007 Elsevier Ltd. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.bmcl.2007.08.078
dc.sourceScopus
dc.subjectCell proliferation
dc.subjectMDA-MB-231
dc.subjectTrisubstituted benzimidazole
dc.typeArticle
dc.contributor.departmentANATOMY
dc.description.doi10.1016/j.bmcl.2007.08.078
dc.description.sourcetitleBioorganic and Medicinal Chemistry Letters
dc.description.volume18
dc.description.issue1
dc.description.page432-435
dc.description.codenBMCLE
dc.identifier.isiut000253720300080
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