Please use this identifier to cite or link to this item: https://doi.org/10.1242/dev.071209
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dc.titleEpithelial-mesenchymal transitions: Insights from development
dc.contributor.authorLim, J.
dc.contributor.authorThiery, J.P.
dc.date.accessioned2014-12-12T08:04:32Z
dc.date.available2014-12-12T08:04:32Z
dc.date.issued2012-10-01
dc.identifier.citationLim, J., Thiery, J.P. (2012-10-01). Epithelial-mesenchymal transitions: Insights from development. Development (Cambridge) 139 (19) : 3471-3486. ScholarBank@NUS Repository. https://doi.org/10.1242/dev.071209
dc.identifier.issn09501991
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/117347
dc.description.abstractEpithelial-mesenchymal transition (EMT) is a crucial, evolutionarily conserved process that occurs during development and is essential for shaping embryos. Also implicated in cancer, this morphological transition is executed through multiple mechanisms in different contexts, and studies suggest that the molecular programs governing EMT, albeit still enigmatic, are embedded within developmental programs that regulate specification and differentiation. As we review here, knowledge garnered from studies of EMT during gastrulation, neural crest delamination and heart formation have furthered our understanding of tumor progression and metastasis. © 2012. Published by The Company of Biologists Ltd.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1242/dev.071209
dc.sourceScopus
dc.subjectEpithelial-mesenchymal transition
dc.subjectGastrulation
dc.subjectHeart morphogenesis
dc.subjectNeural crest
dc.typeReview
dc.contributor.departmentCANCER SCIENCE INSTITUTE OF SINGAPORE
dc.description.doi10.1242/dev.071209
dc.description.sourcetitleDevelopment (Cambridge)
dc.description.volume139
dc.description.issue19
dc.description.page3471-3486
dc.description.codenDEVPE
dc.identifier.isiut000308391400002
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