Please use this identifier to cite or link to this item: https://doi.org/10.1021/ac4039652
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dc.titleLipidomic "deep profiling": An enhanced workflow to reveal new molecular species of signaling lipids
dc.contributor.authorNarayanaswamy, P.
dc.contributor.authorShinde, S.
dc.contributor.authorSulc, R.
dc.contributor.authorKraut, R.
dc.contributor.authorStaples, G.
dc.contributor.authorThiam, C.H.
dc.contributor.authorGrimm, R.
dc.contributor.authorSellergren, B.
dc.contributor.authorTorta, F.
dc.contributor.authorWenk, M.R.
dc.date.accessioned2014-12-12T07:49:51Z
dc.date.available2014-12-12T07:49:51Z
dc.date.issued2014
dc.identifier.citationNarayanaswamy, P., Shinde, S., Sulc, R., Kraut, R., Staples, G., Thiam, C.H., Grimm, R., Sellergren, B., Torta, F., Wenk, M.R. (2014). Lipidomic "deep profiling": An enhanced workflow to reveal new molecular species of signaling lipids. Analytical Chemistry 86 (6) : 3043-3047. ScholarBank@NUS Repository. https://doi.org/10.1021/ac4039652
dc.identifier.issn15206882
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/116436
dc.description.abstractCurrent mass spectrometry-based lipidomics aims to comprehensively cover wide ranges of lipid classes. We introduce a strategy to capture phospho-monoester lipids and improve the detection of long-chain base phosphates (LCB-Ps, e.g., sphingosine-1-phosphate). Ten novel LCB-Ps (d18:2, t20:1, odd carbon forms) were discovered and characterized in tissues from human and mouse, as well in D. melanogaster and S. cerevisiae. These findings have immediate relevance for our understanding of sphingosine-1-phosphate biosynthesis, signaling, and degradation. © 2014 American Chemical Society.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1021/ac4039652
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentMECHANOBIOLOGY INSTITUTE
dc.description.doi10.1021/ac4039652
dc.description.sourcetitleAnalytical Chemistry
dc.description.volume86
dc.description.issue6
dc.description.page3043-3047
dc.description.codenANCHA
dc.identifier.isiut000333235700031
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