Please use this identifier to cite or link to this item:
|dc.title||Strategies for genome reduction in microbial genomes.|
|dc.identifier.citation||Sakharkar, K.R., Chow, V.T. (2005). Strategies for genome reduction in microbial genomes.. Genome informatics. International Conference on Genome Informatics. 16 (2) : 69-75. ScholarBank@NUS Repository.|
|dc.description.abstract||Niche dependent differential gene loss and overlapping genes have been proposed as means of achieving genome reduction by retaining indispensable genes and compressing maximum amount of information in available sequence space. Herein, we analyzed the differential gene loss and overlapping genes in bacterial genomes with different lifestyles. Our results clearly suggest that gene loss and overlapping genes could be a result of evolutionary pressure to minimize genome size. Comparative analysis of the genomes shows that the genomes display marked similarities in patterns of protein length and frequency. It is clear from our analysis that habitat is a major factor contributing to genome reduction. These comparisons increase our knowledge of the forces that drive the extreme specialization of the bacteria and its association to the host.|
|dc.contributor.department||INSTITUTE OF SYSTEMS SCIENCE|
|dc.description.sourcetitle||Genome informatics. International Conference on Genome Informatics.|
|Appears in Collections:||Staff Publications|
Show simple item record
Files in This Item:
There are no files associated with this item.
checked on May 12, 2022
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.