Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/115877
DC Field | Value | |
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dc.title | Positioning and maintenance of embryonic body wall muscle attachments in C. elegans requires the mup-1 gene | |
dc.contributor.author | Goh, P.-Y. | |
dc.contributor.author | Bogaert, T. | |
dc.date.accessioned | 2014-12-12T07:33:36Z | |
dc.date.available | 2014-12-12T07:33:36Z | |
dc.date.issued | 1991-03 | |
dc.identifier.citation | Goh, P.-Y.,Bogaert, T. (1991-03). Positioning and maintenance of embryonic body wall muscle attachments in C. elegans requires the mup-1 gene. Development 111 (3) : 667-681. ScholarBank@NUS Repository. | |
dc.identifier.issn | 09501991 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/115877 | |
dc.description.abstract | As part of a general study of genes specifying a pattern of muscle attachments, we identified and genetically characterised mutants in the mup-1 gene. The body wall muscles of early stage mup-1 embryos have a wild-type myofilament pattern but may extend ectopic processes. Later in embryogenesis, some body wall muscles detach from the hypodermis. Genetic analysis suggests that mup-1 has both a maternal and a zygotic component and is not required for postembryonic muscle growth and attachment. mup-1 mutants are suppressed by mutations in several genes that encode extracellular matrix components. We propose that mup-1 may encode a cell surface/extracellular matrix molecule required both for the positioning of body wall muscle attachments in early embryogenesis and the subsequent maintenance of these attachments to the hypodermis until after cuticle synthesis. | |
dc.source | Scopus | |
dc.subject | Caenorhabditis elegans | |
dc.subject | mup-1 gene | |
dc.subject | Muscle attachment pattern | |
dc.type | Article | |
dc.contributor.department | INSTITUTE OF MOLECULAR & CELL BIOLOGY | |
dc.description.sourcetitle | Development | |
dc.description.volume | 111 | |
dc.description.issue | 3 | |
dc.description.page | 667-681 | |
dc.description.coden | DEVPE | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
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