A new method on gene selection for tissue classification

Abstract

Tumor classification is one of the important applications of microarray technology. In gene expression-based tumor classification systems, gene selection is a main and very important component. In this paper, we propose a new approach for gene selection. With the genes selected in colon cancer data, acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) data using our approach, we apply support vector machines to classify tissues in these two data sets, respectively. The results of classification show that our method is very useful and promising.