Please use this identifier to cite or link to this item: https://doi.org/10.1093/aje/kwi272
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dc.titleVariation in the seasonal diagnosis of acute lymphoblastic leukemia: Evidence from Singapore, the United States, and Sweden
dc.contributor.authorGao, F.
dc.contributor.authorNordin, P.
dc.contributor.authorKrantz, I.
dc.contributor.authorChia, K.-S.
dc.contributor.authorMachin, D.
dc.date.accessioned2014-12-01T06:57:33Z
dc.date.available2014-12-01T06:57:33Z
dc.date.issued2005-10
dc.identifier.citationGao, F., Nordin, P., Krantz, I., Chia, K.-S., Machin, D. (2005-10). Variation in the seasonal diagnosis of acute lymphoblastic leukemia: Evidence from Singapore, the United States, and Sweden. American Journal of Epidemiology 162 (8) : 753-763. ScholarBank@NUS Repository. https://doi.org/10.1093/aje/kwi272
dc.identifier.issn00029262
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/113709
dc.description.abstractThis study investigated, by summing data over successive years, the evidence for the seasonal diagnosis of acute lymphoblastic leukemia. To do so, the authors estimated the dates of peak diagnosis over a range of geographic locations including Singapore (1968-1999), Hawaii and mainland United States (1973-1999), and western Sweden (1977-1994) at latitudes of 1.16°N to 58.24°N. In contrast to other studies, the authors used case-by-case information on dates, gender, and age rather than grouped data for analysis. The seasonal pattern was estimated by fitting a von Mises distribution to the data from each location. No seasonal pattern was found in Singapore, which is close to the equator and does not have marked climatic changes. Likewise, seasonality was not demonstrated in Hawaii or mainland United States despite a 26.18° range of latitudes. In contrast, a significant peak (early January) was observed for western Sweden that appeared strongest for males (December 22, 95% confidence interval: November 16, January 16) and those less than age 20 years (January 14, 95% confidence interval: December 8, March 27). Thus, despite a wide geographic range of localities, there is little evidence of any seasonality in the diagnosis of acute lymphoblastic leukemia in most populations studied and no strong evidence of any influence of climate (as expressed by latitude). Copyright © 2005 by the Johns Hopkins Bloomberg School of Public Health. All rights reserved.
dc.sourceScopus
dc.subjectLeukemia, lymphoblastic, acute
dc.subjectSeasons
dc.typeArticle
dc.contributor.departmentCOMMUNITY,OCCUPATIONAL & FAMILY MEDICINE
dc.description.doi10.1093/aje/kwi272
dc.description.sourcetitleAmerican Journal of Epidemiology
dc.description.volume162
dc.description.issue8
dc.description.page753-763
dc.description.codenAJEPA
dc.identifier.isiut000232423000007
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