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Please use this identifier to cite or link to this item: https://doi.org/10.1016/S1383-5718(02)00274-7
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dc.titleThe associations among semen quality, oxidative DNA damage in human spermatozoa and concentrations of cadmium, lead and selenium in seminal plasma
dc.contributor.authorXu, D.-X.
dc.contributor.authorShen, H.-M.
dc.contributor.authorZhu, Q.-X.
dc.contributor.authorChua, L.
dc.contributor.authorWang, Q.-N.
dc.contributor.authorChia, S.-E.
dc.contributor.authorOng, C.-N.
dc.date.accessioned2014-12-01T06:57:08Z
dc.date.available2014-12-01T06:57:08Z
dc.date.issued2003-01-10
dc.identifier.citationXu, D.-X., Shen, H.-M., Zhu, Q.-X., Chua, L., Wang, Q.-N., Chia, S.-E., Ong, C.-N. (2003-01-10). The associations among semen quality, oxidative DNA damage in human spermatozoa and concentrations of cadmium, lead and selenium in seminal plasma. Mutation Research - Genetic Toxicology and Environmental Mutagenesis 534 (1-2) : 155-163. ScholarBank@NUS Repository. https://doi.org/10.1016/S1383-5718(02)00274-7
dc.identifier.issn13835718
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/113672
dc.description.abstractTo explore the associations among semen quality, oxidative DNA damage in human spermatozoa and concentrations of cadmium, lead and selenium in seminal plasma, 56 non-smoking subjects were asked to collect semen by masturbation into a sterile wide-mouth metal-free plastic container after 3 days of abstinence. The conventional semen parameters were analysed. The concentrations of Cd, Pb and Se in seminal plasma were detected using atomic absorption spectrophotometer. 8-OHdG levels in sperm DNA were measured using HPLC-EC. The results showed that the geometric mean concentrations of Cd, Pb and Se were 0.78, 7.8 and 51.4μg/l, respectively. The geometric mean of 8-OHdG/106 dG was 51.4 (95% CI: 21.5-123.0). A significant inverse correlation exists between Cd and sperm density (r=-0.28, P
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/S1383-5718(02)00274-7
dc.sourceScopus
dc.subject8-Hydroxy-2′-deoxyguanosine
dc.subjectCadmium
dc.subjectDNA damage
dc.subjectLead
dc.subjectSelenium
dc.subjectSpermatozoa
dc.typeArticle
dc.contributor.departmentCOMMUNITY,OCCUPATIONAL & FAMILY MEDICINE
dc.description.doi10.1016/S1383-5718(02)00274-7
dc.description.sourcetitleMutation Research - Genetic Toxicology and Environmental Mutagenesis
dc.description.volume534
dc.description.issue1-2
dc.description.page155-163
dc.description.codenMRGMF
dc.identifier.isiut000180602800015
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