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Title: Effects of an acaricide on mite allergen levels in the homes of asthmatic children
Authors: Chew, F.-T. 
Goh, D.Y.-T.
Lee, B.-W.
Keywords: acaricide
dust mite allergens
Issue Date: 1996
Citation: Chew, F.-T.,Goh, D.Y.-T.,Lee, B.-W. (1996). Effects of an acaricide on mite allergen levels in the homes of asthmatic children. Acta Paediatrica Japonica (Overseas Edition) 38 (5) : 483-488. ScholarBank@NUS Repository.
Abstract: Previous study by the current authors has shown that treating homes with D'Allergen, an acaricidal agent, can reduce bronchial hyper-reactivity in asthmatic children with house dust mite allergy. In the present study, the effects of a single D'Allergen treatment on the levels of major dust mite allergens, Der p I and Der f I was evaluated, and the duration of its effectiveness in the environment determined. Twenty randomly selected homes were treated with the acaricide and ten remained untreated. Dust samples were collected from mattresses, upholstered sofas and carpets of these homes before and 1, 2 and 4 months after treatment. The samples were then assayed for Der p I and Der f I allergens using a sandwich enzyme immunoassay. The results showed that D'Allergen was effective in reducing dust mite allergen levels in all three niches by 1.5-22.3 times below baseline values. This effect, however, was only present for 2 months, and the dust mite allergen levels increased to those of the baseline by the fourth month after treatment. These results indicated that repeated applications of the acaricide were required at 2-3 monthly intervals to obtain optimal effectiveness.
Source Title: Acta Paediatrica Japonica (Overseas Edition)
ISSN: 03745600
Appears in Collections:Staff Publications

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