Please use this identifier to cite or link to this item:
Title: Changing prevalence of gastroesophageal reflux with changing time: Longitudinal study in an Asian population
Authors: Lim, S.L.
Goh, W.T.
Lee, J.-M.J. 
Ng, T.P.
Ho, K.-Y.
Keywords: Acid regurgitation
Gastroesophageal reflux
Issue Date: Jul-2005
Citation: Lim, S.L., Goh, W.T., Lee, J.-M.J., Ng, T.P., Ho, K.-Y. (2005-07). Changing prevalence of gastroesophageal reflux with changing time: Longitudinal study in an Asian population. Journal of Gastroenterology and Hepatology (Australia) 20 (7) : 995-1001. ScholarBank@NUS Repository.
Abstract: Background: The purpose of the present paper was to study previously obtained population-based data on the prevalence of reflux symptoms in a random sample of community adults in Singapore. This sample was re-investigated 5 years later to determine changes in the prevalence of reflux symptoms. Methods: In 1999, 237 (34%) of the original cohort of 696 persons who were interviewed in 1994, were re-interviewed using a validated Gastrointestinal Symptoms Questionnaire. The original cohort was a race-stratified random sample of residents in a Singaporean town. Reflux was defined as heartburn and/or acid regurgitation occurring at least once a month. Results: Among the 237 respondents (aged 25-89 years; male: female, 49:51; Chinese n = 106, 45%; Malay n = 69, 29%; Indian n = 60, 25%), reflux was reported by 25 respondents, giving a prevalence of 10.5 ± 2.0%. This compared with the prevalence of 5.5 ± 1.5% (odds ratio [OR], 2.2; 95% confidence interval [CI]: 1.0-5.2; P = 0.05) among the same 237 respondents in the 1994 survey. Of the 25 subjects who reported reflux in the current survey, 22 (88.0%) did not complain of reflux symptoms in the 1994 survey. The ethnic-adjusted prevalence of reflux in 1999 was estimated to be 9.9 ± 1.9%. This was an increase above the prevalence in 1994 of 1.6 ± 1.0% (P = 0.051). The upward trend in the prevalence of reflux was not related to age, smoking, alcohol consumption, or increase in bodyweight. Conclusions: There is a rising trend of reflux symptoms frequency in the general population of Singapore over a 5-year period. © 2005 Blackwell Publishing Asia Pty Ltd.
Source Title: Journal of Gastroenterology and Hepatology (Australia)
ISSN: 08159319
DOI: 10.1111/j.1400-1746.2005.03887.x
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.


checked on Jan 26, 2023

Page view(s)

checked on Jan 26, 2023

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.