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https://doi.org/10.1002/1097-0290(2000)71:23.0.CO;2-7
| Title: | A selenide linker for "Traceless" solid-phase organic synthesis | Authors: | Li, Z. Kulkarni, B.A. Ganesant, A. |
Keywords: | Selenides Solid-phase synthesis Traceless linkers |
Issue Date: | 2000 | Citation: | Li, Z.,Kulkarni, B.A.,Ganesant, A. (2000). A selenide linker for "Traceless" solid-phase organic synthesis. Biotechnology and Bioengineering 71 (2) : 104-106. ScholarBank@NUS Repository. https://doi.org/10.1002/1097-0290(2000)71:23.0.CO;2-7 | Abstract: | 4-Bromophenethyl alcohol was protected as the THP ether, followed by reaction with magnesium and selenium to give the corresponding diselenide. Ether deprotection provides a diselenide diol, which is attached to solid-phase resins. The polymer-bound selenide anion is then generated, and functions as a traceless linker for electrophiles such as alkyl halides. © 2001 John Wiley & Sons, Inc. | Source Title: | Biotechnology and Bioengineering | URI: | http://scholarbank.nus.edu.sg/handle/10635/111767 | ISSN: | 00063592 | DOI: | 10.1002/1097-0290(2000)71:23.0.CO;2-7 |
| Appears in Collections: | Staff Publications |
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