Please use this identifier to cite or link to this item: https://doi.org/10.1002/1522-7189(199911/12)7:6<361::AID-NT79>3.0.CO;2-1
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dc.titleDetection of diarrhetic shellfish poisoning toxins from tropical shellfish using liquid chromatography-selected reaction monitoring mass spectrometry
dc.contributor.authorHolmes, M.J.
dc.contributor.authorTeo, S.L.M.
dc.contributor.authorKhoo, H.W.
dc.date.accessioned2014-11-28T02:12:43Z
dc.date.available2014-11-28T02:12:43Z
dc.date.issued1999
dc.identifier.citationHolmes, M.J., Teo, S.L.M., Khoo, H.W. (1999). Detection of diarrhetic shellfish poisoning toxins from tropical shellfish using liquid chromatography-selected reaction monitoring mass spectrometry. Natural Toxins 7 (6) : 361-364. ScholarBank@NUS Repository. https://doi.org/10.1002/1522-7189(199911/12)7:6<361::AID-NT79>3.0.CO;2-1
dc.identifier.issn10569014
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/111722
dc.description.abstractA negative mode liquid chromatography-selected reaction monitoring mass spectrometry (LC-SRM MS) method was developed to detect low concentrations of the diarrhetic shellfish poisoning (DSP) toxins okadaic acid and dinophysistoxin-1 (DTX-1). Detection relies upon monitoring the transition of negative precursor ions [M - H]- to a common fragment ion of m/z 255. Our limit of detection for okadaic acid with this method is 0.5 pg on column. LC-SRM MS has allowed us to detect persistent low concentrations of DSP toxins from Singapore shellfish. Copyright © 1999 John Wiley & Sons, Ltd.
dc.sourceScopus
dc.subjectDiarrhetic shellfish poisoning
dc.subjectMass spectrometry
dc.subjectMussels
dc.subjectOkadaic acid
dc.subjectSingapore
dc.typeArticle
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.contributor.departmentBIOSCIENCE CENTRE
dc.description.doi10.1002/1522-7189(199911/12)7:6<361::AID-NT79>3.0.CO;2-1
dc.description.sourcetitleNatural Toxins
dc.description.volume7
dc.description.issue6
dc.description.page361-364
dc.description.codenNATOE
dc.identifier.isiutNOT_IN_WOS
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