Please use this identifier to cite or link to this item: https://doi.org/10.1007/s10353-011-0618-6
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dc.titleShort-term outcomes of lung transplant in idiopathic pulmonary fibrosis
dc.contributor.authorTeo, A.Tk.
dc.contributor.authorPietrobon, R.
dc.contributor.authorAtashili, J.
dc.contributor.authorRajgor, D.
dc.contributor.authorShah, J.
dc.contributor.authorMartins, H.
dc.date.accessioned2014-11-26T08:30:27Z
dc.date.available2014-11-26T08:30:27Z
dc.date.issued2011-10
dc.identifier.citationTeo, A.Tk., Pietrobon, R., Atashili, J., Rajgor, D., Shah, J., Martins, H. (2011-10). Short-term outcomes of lung transplant in idiopathic pulmonary fibrosis. European Surgery - Acta Chirurgica Austriaca 43 (5) : 284-294. ScholarBank@NUS Repository. https://doi.org/10.1007/s10353-011-0618-6
dc.identifier.issn16828631
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/110267
dc.description.abstractBackground: Idiopathic pulmonary fibrosis (IPF) is currently the main indication for lung transplant (LTx) in the United States. Opinions differ regarding the outcomes in IPF compared to other conditions. This study compares the short-term outcomes of LTx in IPF versus non-IPF as well as single lung transplant (SLT) versus bilateral lung transplant (BLT) in IPF patients in a large nationally representative sample. Methods: We performed a secondary analysis of the Nationwide Inpatient Sample (1988-2006). Patients aged 21 and above who underwent LTx during this period were included. The five post-operative outcomes evaluated were inpatient mortality (IM), transplant-related complications (TC), non-transplant related (NTC) complications during inpatient stay, length of stay (LOS) more than 14 days and any non-routine discharge (ND) destination. Results: There were 1845 patients who underwent LTx during the analysis period. Controlling for confounders, and compared to non-IPF patients, IPF patients were more likely to be in hospital more than 14 days (OR=1.75; 95% CI =1.31, 2.36; p≤0.001); as likely to have inpatient mortality (OR=1.00; 95% CI=0.58, 1.72) and non-routine discharge (OR=0.95; 95% CI=0.73, 1.50); and not significantly less likely to have transplant-related complications (OR = 0.82; 95% CI = 0.57, 1.17) and non-transplant related complications (OR =0.89; 95% CI = 0.65, 1.22). IPF patients who underwent BLT were significantly more likely to develop transplant-related complications (OR=2.52; 95% CI =1.06, 5.97; p=0.035) and non-transplant related complications (OR =2.22; 95% CI= 1.17, 4.24; p=0.015); and not significantly more likely to have inpatient mortality (OR=2.24; 95% CI=0.80, 6.27), length of stay longer than 14 days (OR=1.84; 95% CI=0.83, 4.11) and nonroutine discharge (OR= 1.15; 95% CI =0.44, 1.69). Conclusions: This paper demonstrated that in this population of patients in the United States, there was an increased risk of greater LOS for IPF patients. BLT in IPF patients had a significantly higher risk for inpatient complications. © Springer-Verlag 2011.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1007/s10353-011-0618-6
dc.sourceScopus
dc.subjectIdiopathic pulmonary fibrosis
dc.subjectLung transplant
dc.subjectMorbidity
dc.subjectMortality
dc.subjectPost-operative complications
dc.typeArticle
dc.contributor.departmentDUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE
dc.description.doi10.1007/s10353-011-0618-6
dc.description.sourcetitleEuropean Surgery - Acta Chirurgica Austriaca
dc.description.volume43
dc.description.issue5
dc.description.page284-294
dc.description.codenESUUB
dc.identifier.isiut000297367700006
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